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Silicone Breast Implant Ban Lifted On November 17, the US Food and Drug Administration approved the use of silicone gel breast implants for breast reconstruction in all women and for cosmetic breast augmentation in women aged 22 and older, lifting a 14-year ban. Do you favor or oppose this decision? To vote or view results of the poll, click on the title above.  Commentary -- End the War on Obesity: Make Peace With Your Patients
Linda Bacon, MA, PhD, a Nutrition Professor and a Nutritionist, explains why healthy lifestyle habits are more important than the numbers on the scale. Medscape General Medicine 8(4) 2006 Torcetrapib Torpedoed: Increased Risk of Mortality, Cardiovascular Events Ends Development Pfizer has halted its torcetrapib development program after it learned there was an "imbalance of mortality and cardiovascular events" in a major morbidity and mortality trial testing the drug in combination with atorvastatin vs atorvastatin alone in subjects with coronary heart disease or risk equivalents. While the drug has been plagued by blood-pressure increases, little is yet known why the once-promising drug went off the rails. Heartwire2006 Best Practices for Atrial Fibrillation Ablation Catheter ablation for AF -- read how far we've come and what the future will likely bring. What are the differences between selective and dual endothelin receptor antagonists? This review looks at the evolving complexities in selecting a treatment for PAH. Marathon Runners Should Reduce Sun Exposure to Avoid Malignant Melanoma Marathon runners should wear adequate clothing and choose training times with low sun exposure to reduce the risk of developing malignant melanoma and other skin cancers. Medscape Medical News2006 This study supports the effectiveness of famciclovir, but head-to-head studies are needed to answer more questions. A changing mole can be an urgent dermatologic concern, but did patients with this problem get a timely appointment with a dermatologist? Insulin Therapy: Indications, Insulin Types, and Treatment Design Healthcare providers need to recognize that over time many patients with type 2 diabetes will require insulin to achieve therapeutic targets. In a large cohort of men with type 2 diabetes, smoking significantly increased the risk for low glomerular filtration rate, which was at least partially mediated by metabolic syndrome. Conference Report -- Trauma Update: American College of Emergency Physicians Meeting An overview of 2 key lectures: Dr. Andrew Perron on the use of CT scanning in trauma, and Dr. Swaminatha Mahadevan's review and discussion of the most clinically relevant trauma-management articles. Medscape Critical Care 7(2) 2006  Methadone-Related Fatalities Underscore Need for Careful Dosing
Inadvertent systemic accumulation of methadone (Dolophine) can increase the risk for respiratory depression and cardiac arrhythmias. Medscape Medical News 2006 In a group of premenopausal women, the association between body mass index at age 18 years and incident breast cancer was stronger for those with estrogen-receptor��positive tumors. Conference Coverage -- American College of Gastroenterology 2006 Annual Scientific Meeting and Postgraduate Course Leading authorities provide clinically focused and comprehensive updates on topical issues in the fields of gastroenterology and hepatology, based on selected sessions at ACG 2006. The patient is a 20-year-old white woman with mild-to-moderate acute pancreatitis, with febrile illness and progressive elevation of peripheral WBC count. John Baillie, MD, explores the issues. One-Dose Antibiotic Regimen Effectively Prevents Surgical Site Infections Compared with 24-hour prophylaxis, 1-dose antibiotic prophylaxis did not lead to an increase in rates of surgical site infections and saved $1980 monthly. Medscape Medical News2006 A Comparative Study of HIV/AIDS: The Knowledge, Attitudes, and Risk Behaviors of Schizophrenic and Diabetic Patients in Regard to HIV/AIDS in Nigeria Patients with schizophrenia had more misconceptions about HIV/AIDS, were less tolerant towards people living with HIV/AIDS compared with diabetic patients, and more likely to place themselves at risk. Medscape General Medicine 8(4) 2006 This was the first randomized trial of STI for patients with MDR HIV and treatment failure with a clinical end point, allowing investigators to determine the long-term impact of STI in this setting. Mantle Cell Lymphoma: An Update for Clinicians Read this comprehensive review to stay up to date on all of the most recent advances in the treatment of patients with mantle cell lymphoma. Influenza and the Elderly Patient Diagnosis and treatment of influenza in an elderly person require an approach and clinical perspective that differ from the evaluation and management appropriate for younger individuals. Some ducks and gulls are highly susceptible to infection with H5N1 HPAI viruses as evidenced by widespread microscopic lesions, prolonged and highly concentrated viral shedding, and seroconversion. In a randomized trial, an early switch from intravenous to oral antibiotics was effective in reducing hospital stay in those with severe community-acquired pneumonia. Intentional Weight Loss and Gain May Raise Men's Risk for Gallstones A prospective study suggests that men who have cycles of intentional weight loss and weight gain may increase their risk for gallstone disease. Medscape Medical News2006 Review the best evidence on the comparative effectiveness of NSAIDs and other analgesics for osteoarthritis. Are proton pump inhibitors more effective than ranitidine in health ulcers associated with NSAIDs? Teaching and Learning Online: Notes From Dr. RW A hospitalist from Arkansas finds that blogging offers a way to stay in touch with the larger medical world when the constraints of everyday practice intervene. Medscape Med Students 8(2) 2006 A week after initiating therapy for cryptococcal meningitis, the patient is found to be confused. Can you figure out the problem? Conference Coverage -- Renal Week 2006: American Society of Nephrology Annual Meeting Among patients at high risk for kidney disease, obesity is linked with lower mortality; hypertension in pregnancy linked to increased risk for CVD, microalbuminuria. Read clinically focused news coverage of key developments from the meeting. What Are the Current Guidelines About Wearing Artificial Nails and Nail Polish in the Healthcare Setting? I have a colleague who still wears artificial nails at work. What is the latest evidence about wearing artificial nails and nail polish in the healthcare setting? Medscape Nurses 8(2) 2006 Pacifier thermometers: What's the evidence? Early recognition and treatment is vital. Learn more about serotonin syndrome here. Simvastatin May Help Ameliorate Polycystic Ovary Syndrome A small randomized controlled trial showed that simvastatin improved endocrine/clinical aspects of PCOS and had beneficial effects on lipid profile and markers of systemic inflammation. Medscape Medical News2006 Maximizing the Safety of Intravitreal Injections Promising new treatments for retinal diseases require intravitreal injections. Drs. Alexander Brucker and Tim Hopkins review strategies for decreasing the risk of injection-related complications. Medscape Ophthalmology 7(2) 2006 Floaters are a common presenting ophthalmic symptom that may accompany sight-threatening disorders. How to distinguish and how to manage debilitating floaters? Quadriceps Strength May Decrease 4 Years After Knee Surgery Quadriceps strength was reduced in the meniscectomized leg vs the nonoperated leg 4 years after surgery, contributing to limited knee function, pain, and reduced quality of life. Medscape Medical News2006 Differential Usefulness of Various Markers in the Flow Cytometric Detection of Paroxysmal Nocturnal Hemoglobinuria in Blood and Bone Marrow This study demonstrated the usefulness of a marker combination in detecting glycosyl phosphatidylinositol (GPI)-deficient monocytes and granulocytes in bone marrow specimens. Am J Clin Pathol 126(5) 2006 In some cases of otherwise typical myelodysplastic syndrome (MDS), progenitor cells may have some capacity for monocytic proliferation at diagnosis and manifest rapid disease progression.  Conference Coverage -- American Academy of Pediatrics 2006 National Conference and Exhibition
AAP 2006: William Basco, MD, looks at new research on UTI, asthma and allergy, passenger safety, infections, fevers, and more. Implementation of PCV7, combined with a reduction in antibiotic use, appears to have a strong impact on the carriage of penicillin nonsusceptible pneumococci in children with AOM. In an observational study, breast-feeding was linked to resilience against psychosocial stress, such as parental divorce, in children. FDA Approvals: Inamed and MemoryGel The FDA has approved silicone breast implants (Inamed and MemoryGel) for breast reconstruction in women of all ages and for breast augmentation in those aged 22 years and older. Medscape Medical News2006 The FDA has approved safety labeling revisions for dexmethylphenidate, methylphenidate, and interferon-alfa-2a. The high volume of patients passing through hospital emergency rooms presents a distinct public health opportunity. Alcohol Dependence: The Importance of Neurobiology to Treatment George F. Koob, PhD, discusses the biological basis of different aspects of alcohol dependence. Medscape Psychiatry & Mental Health 11(2) 2006 Population-Level Changes in Folate Intake by Age, Gender, and Race/Ethnicity after Folic Acid Fortification A national mandate to fortify all enriched grain products with folic acid has led to an overall intake of the nutrient, yet consumption still falls short of targets and varies among populations. Am J Public Health 96(11) 2006 Upward social mobility helps lower risk of low birthweight, but not for black women, according to a new study involving more than 1,800 births. Lung Transplantation for Cystic Fibrosis An update on changes in surgical techniques, selection criteria of patients, and impact on quality of life in CF. Curr Opin Pulm Med 12(6) 2006 Conference Coverage -- Radiological Society of North America 92nd Scientific Assembly and Annual Meeting No benefit to adding spectroscopy to MRI for localization of peripheral zone prostate cancer; liquid silicone injections can have lethal consequences. Read clinically focused news coverage of key developments from the meeting. A young, sexually active woman presented for a pelvic magnetic resonance imaging (MRI) study as a component of an infertility workup following an abnormal physical examination and ultrasound study. Cytotoxic and Glucocorticoid Agents Increase CV Risk in Rheumatoid Arthritis In a nested case-control study, immunosuppressive biologic agents did not affect risk vs methotrexate, but oral glucocorticoids and cytotoxic immunosuppressants did increase CV risk. Medscape Medical News2006 The Effect Of Tadalafil On Psychosocial Outcomes In Swedish Men With Erectile Distress: A Multicentre, Non-Randomised, Open-Label Clinical Study Tadalafil led to improvements in satisfaction with intimate relations and family life and a reduction in manifest erectile distress. Int J Clin Pract 60(11) 2006 In this Review the authors discuss radioisotope-guided sentinel lymph node dissection in prostate cancer staging. The early results are promising. Information from Industry Medical Comorbidities in Mental Illness- View an interactive program presented by Walter Byrd, MD, and Michael Bush, MD, illustrating the importance of monitoring blood glucose in mentally ill patients. http://mp.medscape.com/cgi-bin1/DM/y/hBDkW0SapLk0Dyv0FqjA0Et |
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