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Medical News Update from News-Medical.Net - 4th February 2007

Probing proteins can lead to better understanding of anti-tumor agents
//Medical Research News
There are a number of naturally occurring chemicals that are used in phototherapy of skin diseases. Hypocrellin A (HA), which can be extracted from a parasitic fungus, has been taken orally as a folk medicine for several centuries in China.
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Discovery of pancreatic cancer stem cells could lead to more effective therapies
//Medical Research News
Scientists in the United States have identified for the first time the stem cells linked to pancreatic cancer.
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Cruelty-free ELISA for human insulin
//Medical Research News
In the January issue of Clinical Biochemistry, scientists and physicians with the Physicians Committee for Responsible Medicine (PCRM) outline the method used to develop a cruelty-free ELISA for human insulin that uses monoclonal antibodies produced by cells cultured in an animal-serum-free medium.
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New understanding of cholera pathogen
//Medical Research News
Researchers at Rensselaer Polytechnic Institute have discovered new details about how bacteria generate energy to live. In two recently published papers, the scientists add key specifics to the molecular mechanism behind the pathogen that causes cholera.
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Dll4 signalling through Notchi regulates formation of tip cells during angiogenesis
//Medical Research News
All tissues, sick and healthy alike, need a blood supply to survive and grow. The key to many medical problems, like preventing tumour development, is therefore to obstruct the spread of the blood vessels. Research scientists at Karolinska Institutet have now discovered a heretofore unknown mechanism for how the body links together its blood vessels.
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Gene produces springy protein keeping nerve cells flexible
//Medical Research News
If you bend a knee or an elbow, the nerves in your limbs stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny nematode worms, their nerve cells literally broke.
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Antibiotic doses could be reduced by up to 50 times using new approach
//Medical Research News
Steven Hagens, previously at the University of Vienna, told Chemistry & Industry, the magazine of the SCI, that certain bacteriophages, a type of virus that infects bacteria, can boost the effectiveness of antibiotics gentamicin, gramacidin or tetracycline.
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Scientists tackle huntingtin protein
//Medical Research News
McMaster scientists are very close to defining small molecule drugs that should be able to redirect the huntingtin protein from accumulating in the wrong place within brain cells, which could potentially translate to a therapy for Huntington's Disease (HD).
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Stroke risk for sickle cell children with early complications
//Medical Research News
Children with sickle cell disease who experienced major complications such as pain and lung disease early in life are at no greater risk for stroke or death during later childhood, new research from UT Southwestern Medical Center shows.
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A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis
//Medical Research News
Marked by chronic inflammation of the joints and tissue, rheumatoid arthritis (RA) is a painful and potentially disabling autoimmune disease.
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CeNeRx BioPharma starts human trials of RIMA antidepressant
//Medical Studies/Trials
CeNeRx BioPharma, Inc. has announced the initiation of human clinical trials of Tyrima, CeNeRx's new drug candidate with a triple mechanism of action for the treatment of depression and anxiety.
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Risperidone may help people with autism
//Medical Studies/Trials
Risperidone, a drug used to control schizophrenia symptoms, may also help treat behaviors found in autism spectrum disorder, according to a new review of studies.
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Investigational treatment for cervical dysplasia
//Medical Studies/Trials
Temple University Hospital's Center For Women's Health is participating in a national study to determine the safety and effectiveness of an investigational treatment for cervical dysplasia.
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Magnetic resonance angiography of supraaortic arteries
//Medical Studies/Trials
A novel type of contrast-enhanced magnetic resonance (MR) angiography is highly accurate in identifying blockages in the arteries that carry blood to the brain, according to a study in the February issue of Radiology.
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Creatine could help people with muscular dystrophies
//Medical Studies/Trials
Creatine, a popular nutritional supplement used by weightlifters and sprinters to improve athletic performance, could lend muscle strength to people with muscular dystrophies.
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Psychological effects of heart surgery
//Medical Studies/Trials
Cases of congenital heart disease (CHD), in both adolescents and adults, have been on the rise for many years.
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Startling results from first study of HIV dementia on the Africa
//Medical Studies/Trials
An international study led by Johns Hopkins suggests that the rate of HIV-associated dementia is so high in sub-Saharan Africa that HIV dementia along with Alzheimer's disease and dementia from strokes may be among the most common forms of dementia in the world.
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Time, therapy spur recovery from sudden sensorineural hearing loss
//Medical Studies/Trials
A first-of-its-kind study into time-dependent treatments of sudden sensorineural hearing loss published in the February 2007 issue of Otolaryngology- Head and Neck Surgery has determined that a combination of time and oral corticosteroid therapy can play a key role in helping patients regain full hearing, often within a month of the initial loss of hearing.
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Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women
//Medical Studies/Trials
Aromatase inhibitors, a type of hormone therapy used to treat advanced breast cancer in postmenopausal women, result in a small but significant increase in overall survival when compared to other hormone treatments, according to a new systematic review of studies.
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Studies on heart disease do not provide sex-based analysis
//Medical Studies/Trials
Heart disease differences in men and women continue to be poorly understood because women are included in clinical trials far less than men, and even when women are included, study results are not reported by sex, according to a study in the current issue of Mayo Clinic Proceedings.
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Older womens' risk of heart disease and strokes increased by air pollution
//Women's Health News
A study by researchers in the U.S. has found that air pollution might be a contributing factor in the incidents of heart disease and strokes in older women.
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Damage to muscle during vaginal deliveries connected with pelvic organ prolapse
//Women's Health News
An increase among women electing to have caesarean sections in recent years has been due in large part to a concern that giving birth vaginally will lead to a fallen bladder and uterus in later life, and the issue has been hotly debated in the medical community.
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Women and alcoholism recovery
//Women's Health News
PhD candidate Ms Janice Withnall, from the University of Western Sydney (UWS) School of Education, is carrying out the project in a bid to better understand the experiences of women who have successfully stopped drinking.
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Giving birth to a child naturally increases risk of hemorrhage in newborns
//Women's Health News
The first researchers to use magnetic resonance imaging (MRI) to study the brains of a large group of babies soon after birth found a small amount of bleeding in and around the brains of one in four babies who were delivered vaginally.
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