The Editor at News-Medical.Net editor@news-medical.net

Researchers look at malaria resistance to chloroquine
http://www.news-medical.net/?id=29420
Funded by a $1.5 million grant from the National Institutes of Health (NIH), scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.

Retinoblastoma tumor suppressor may predict chemotherapy effectiveness
http://www.news-medical.net/?id=29425
A common molecular pathway could help physicians predict which lung cancer patients will benefit from chemotherapy drugs, according to new research from a multidisciplinary team at the University of Cincinnati (UC).

University of Utah receives $19.2 Million for HIV research
http://www.news-medical.net/?id=29408
University of Utah biochemist Wesley I. Sundquist, Ph.D., has been awarded a five-year, $19.2 million National Institutes of Health (NIH) grant to establish an HIV research center to study the structural biology of the AIDS-causing virus.

New technique detects specific chromosomal damage - helps identify precancerous changes
http://www.news-medical.net/?id=29404
A new technique could pave the way toward screening people at risk for lung cancer for the genetic changes that may foreshadow malignancies, researchers from the University of Colorado say.

Cell that triggers symptoms in allergy attacks can also limit damage
http://www.news-medical.net/?id=29376
A blood cell known as a troublemaker for triggering the itch and inflammation in allergy attacks, the mast cell, can also calm down the flare-ups, researchers from Stanford University School of Medicine have found.

Genetic variant linked to human height discovered
http://www.news-medical.net/?id=29383
It became clear nearly a century ago that many genes likely influence how tall a person grows, though little progress, if any, has followed in defining the myriad genes. Now an international research team brings light to this age-old question by pinpointing a genetic variant associated with human height - the first consistent genetic link to be reported.

First common height gene identified by researchers behind 'obesity gene' finding
http://www.news-medical.net/?id=29385
Whilst we all know that tall parents are more likely to have tall children, scientists have been unable to identify any common genes that make people taller than others. Now, however, scientists have identified the first gene, known as HMGA2, a common variant of which directly influences height.

New targets for antibiotics
http://www.news-medical.net/?id=29340
University of Illinois at Chicago researchers have identified new sites on the bacterial cell's protein-making machinery where antibiotics can be delivered to treat infections.

Neurotransmitter current not flowing through ion channels
http://www.news-medical.net/?id=29321
In studying how neurotransmitters travel between cells -- by analysis of events in the dimensions of nanometers -- Cornell researchers have discovered that an electrical current thought to be present during that process does not, in fact, exist.

New insights into knee injuries and osteoarthritis in the knee
http://www.news-medical.net/?id=29322
The sort of swelling that occurs when a joint is damaged by injury or degeneration is normally essential to the healing process, but when it comes to the knee, that inflammation can actually interfere with healing.

Small animal imaging facility is big boon to research
http://www.news-medical.net/?id=29333
When powerful magnets line up the body's protons before radiofrequency waves can grab their attention away, it's called spin physics.

Novel methods for the regeneration of musculoskeletal tissues
http://www.news-medical.net/?id=29341
A research group led by Dr. Cato T. Laurencin, with faculty representing five departments at the University of Virginia, will work on a first-of-its kind, $2 million grant project as they explore novel methods for the regeneration of musculoskeletal tissues.

Improving diagnosis of pancreatic cancer
http://www.news-medical.net/?id=29312
In the August issue of Molecular & Cellular Proteomics, scientists provide the first large-scale identification of proteins that are overexpressed in chronic pancreatitis, an inflammatory condition of the pancreas that shares many features with pancreatic cancer.

Protein on the surface of platelets plays a key role in cancer-induced platelet aggregation
http://www.news-medical.net/?id=29314
Scientists have provided new details about how cancer cells spread by surrounding themselves with platelets - the blood cells needed for blood clotting.

Discovery may lead to new class of diabetes drugs
http://www.news-medical.net/?id=29308
A multidisciplinary team led by researchers at the University of California, San Diego has determined the structure of a protein found in cells that shows potential as a target for the development of new drugs to treat diabetes.

HPV vaccines may decrease chances of oral cancer
http://www.news-medical.net/?id=29317
The Centers for Disease Control report that nearly 25 million women are infected with some form of the Human Papilloma Virus (HPV).

New anti-cancer drug made from corn lillies kills brain tumor stem cells
http://www.news-medical.net/?id=29310
A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.

Pancreatic cancer fights off immune attack
http://www.news-medical.net/?id=29327
Scientists of the German Cancer Research Center (Deutsches Krebsforschungszentrum) and the Heidelberg University Hospitals have discovered that pancreatic cancer attracts regulatory T cells, which suppress the activity of immune cells.

Contact disorder makes cancer cells mobile
http://www.news-medical.net/?id=29306
The loss of the protein VMP1 in cancer cells increases their tendency to detach from the initial tumor - the first step towards metastasis.

Binghamton University researchers investigate evolving malaria resistance
http://www.news-medical.net/?id=29302
Funded by a $1.5 million grant from the National Institutes of Health, scientists at Binghamton University, State University of New York, hope to understand how the malaria parasite Plasmodium falciparum evolved resistance to the once-effective medication chloroquine.

Researchers chart the level of gene expression in melanoma cell lines
http://www.news-medical.net/?id=29313
Other than visually inspecting the disease, doctors have no genetic blueprint to classify melanomas, a lethal form of skin cancer.

New method for fighting skin wrinkles
http://www.news-medical.net/?id=29301
A new method for fighting skin wrinkles has been developed at the Hebrew University Faculty of Agriculture, Food and Environmental Quality Sciences.

How neurotransmitters travel between cells
http://www.news-medical.net/?id=29316
In studying how neurotransmitters travel between cells - by analysis of events in the dimensions of nanometers - Cornell researchers have discovered that an electrical current thought to be present during that process does not, in fact, exist.

Researchers explain evolution of lifespan
http://www.news-medical.net/?id=29226
Stanford scientists show in a forthcoming paper that traditional mating patterns make men the key to explaining away the "wall of death," an enduring puzzle in the study of human longevity.

New understanding of endoplasmic reticulum
http://www.news-medical.net/?id=29254
In obese individuals, fat cells are bloated and inflamed because they receive too many nutrients, including lipids.

HPV vaccines may lower risk of oral cancer
http://www.news-medical.net/?id=29224
The Centers for Disease Control report that nearly 25 million women are infected with some form of the Human Papilloma Virus (HPV).

Lipid offers new ways of treating inflammatory kidney diseases
http://www.news-medical.net/?id=29237
Scientists report in the September 2007 issue of the Journal of Lipid Research that a lipid known to protect the heart from inflammation and to cause skin allergic reactions also reduces inflammation of the kidneys.

Skin-healing pseudoceramides
http://www.news-medical.net/?id=29238
Researchers report in the September 2007 issue of the Journal of Lipid Research that they have made synthetic lipids called pseudoceramides that are involved in skin cell growth and could be used in treating skin diseases in which skin cells grow abnormally.

Report on access to cancer drugs across Europe flawed
http://www.news-medical.net/?id=29281
A leading epidemiologist has attacked Swedish research that looked at inequalities in patients' access to cancer drugs across Europe and the world.

Third factor identified in obesity-induced Type 2 diabetes
http://www.news-medical.net/?id=29283
In cases of Type 2 diabetes, the body's cells fail to appropriately regulate blood glucose levels.

Researchers discover what makes lymphomas tick
http://www.news-medical.net/?id=29259
University of Pennsylvania researchers and their colleagues at the Wistar Institute and University of Oxford have discovered the molecular process by which the PAX5 protein, necessary for lymphocyte development, promotes the growth of common lymphomas, thereby unveiling a potential new target in the fight against cancer.

Smoking turns on genes
http://www.news-medical.net/?id=29113
Smoking tobacco is no longer considered sexy, but it may prove a permanent turn on for some genes.

Research looks at hepatitis C recovery
http://www.news-medical.net/?id=29288
More than 3% of world population is infected with hepatitis C virus (HCV). The outcome of HCV infections is either self recovery or chronic hepatitis, and many of the chronic infections will develop into liver cirrhosis or liver cancer.

Autophagy-induced signals are essential for normal development
http://www.news-medical.net/?id=29260
A cannibalistic process called autophagy spurs dying embryonic stem cells to send "eat me" and "come get me" signals to have their corpses purged, a last gasp that paves the way for normal mammalian development, UT Southwestern Medical Center researchers have found.

Researchers unlock mystery of a third olfactory system
http://www.news-medical.net/?id=29287
Researchers at the University of Maryland School of Medicine have found a "nose within the nose," a unique olfactory system within the noses of mice that is able to "smell" hormones involved in regulating water and salt balance in the body.

Big leap in genomic screening of blood vessels from patient tissue
http://www.news-medical.net/?id=29279
Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.

Researchers discover nature uses a recurring molecular strategy to defend against infection
http://www.news-medical.net/?id=29282
With infections increasingly resistant to even the most modern antibiotics, researchers at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) report in the September issue of Nature Reviews Microbiology on new clues they have uncovered in immune system molecules that defend against infection.

Researchers dispute immortal strand hypothesis
http://www.news-medical.net/?id=29286
How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer?

Discovery of key link that causes malarial infection in both humans and mosquitoes
http://www.news-medical.net/?id=29266
As summer temperatures cool in the United States, fewer mosquitoes whir around our tiki torches.

Influence of sex and handedness on brain is similar in capuchin monkeys and humans
http://www.news-medical.net/?id=29271
Capuchin monkeys are playful, inquisitive primates known for their manual dexterity, complex social behavior, and cognitive abilities.

Discovery may lead to fast and cheap method of making vaccines
http://www.news-medical.net/?id=29204
Researchers may be able to tinker with a single amino acid of an enzyme that helps viruses multiply to render them harmless, according to molecular biologists who say the discovery could pave the way for a fast and cheap method of making vaccines.

Risks associated with facial transplantation may be lower than thought
http://www.news-medical.net/?id=29205
Researchers in Cincinnati and Louisville report that immunosuppressive risks associated with facial transplantation may be lower than thought, possibly making the procedure a safer option for people who have suffered severe facial injuries.

Aid boost for hearing research
http://www.news-medical.net/?id=29195
Research at the University of Essex into aiding people with hearing impairments has won a grant of nearly half a million pounds.

China: The aging giant
http://www.news-medical.net/?id=29199
China's efforts to control population growth in the present may cause problems for the county's senior citizens in the future.

New mathematical models for circadian rhythm
http://www.news-medical.net/?id=29148
The internal clock in living beings that regulates sleeping and waking patterns -- usually called the circadian clock -- has often befuddled scientists due to its mysterious time delays.

New understanding of factor YY1 in gene expression
http://www.news-medical.net/?id=29147
The Conaway Lab - led by Joan Conaway, Ph.D., and Ron Conaway, Ph.D., Investigators - has published findings that shed light on the role of the much-studied transcription factor YY1 in gene expression.

Zinc and macular degeneration link
http://www.news-medical.net/?id=29166
A team of scientists, including three researchers at George Mason University, found that the mineral zinc could play a role in the development of macular degeneration.

Breast epithelial cells serve as a barrier against cancer
http://www.news-medical.net/?id=29146
Sheets of highly organized epithelial cells line all the cavities and free surfaces of the body, forming barriers that control the movement of liquids and cells in the body organs.

Secret to bone's strength
http://www.news-medical.net/?id=29158
Scientists and engineers are eager to understand the secret behind bone's lightweight toughness so they can mimic it in the design of new materials, but previous studies have revealed a number of different strength mechanisms at different scales of focus, rather than a single theory.

Pfizer and Bristol-Myers Squibb finalize agreement on metabolic disorders program
http://www.news-medical.net/?id=29164
Pfizer Inc. and Bristol-Myers Squibb Company have announced that they have finalized a definitive agreement for the worldwide collaboration to research, develop and commercialize DGAT-1 inhibitors, a collaboration first announced on April 26, 2007.

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