The Editor at News-Medical.Net editor@news-medical.net

New Jersey appellate court rules referendum asking voters to approve $450M for stem cell research should remain on ballot
http://www.news-medical.net/?id=31941
A three-judge panel of a New Jersey appellate court on Friday unanimously ruled that a Nov. 6 referendum that would allow the state to borrow $450 million over 10 years to fund stem cell research in the state should not be removed from the ballot, the New York Times reports (Peters, New York Times, 10/27).

Saint Louis University scientists identify chemical that triggers Parkinson's disease
http://www.news-medical.net/?id=31928
Researchers at the Saint Louis University School of Medicine have discovered the key brain chemical that causes Parkinson's disease - a breakthrough finding that could pave the way for new, far more effective therapies to treat one of the most common and debilitating neurological disorders.

Copper transporter plays an unexpected role in the absorption of cisplatin
http://www.news-medical.net/?id=31925
Platinum complexes such as the well-known cisplatin are powerful antitumor medications. They cross the cell membrane and reach the nucleus, where they attach to DNA and stop cell growth. But how does cisplatin get to the nucleus?

Unhealthy weight perceptions more unhealthy than unhealthy weight
http://www.news-medical.net/?id=31914
Results soon to be published in the International Journal of Obesity reveal that overweight and underweight perception rather than weight status or weight misperception are significant risk factors associated with medium and high psychological distress in Australian men and women.

What makes some clays powerful antimicrobial agents?
http://www.news-medical.net/?id=31903
With funding from the National Institutes of Health-National Center for Complementary and Alternative Medicine, the UB geologists are studying the surface characteristics of a broad range of naturally occurring antimicrobial clays, including some clays from France to determine why they are such effective killers of bacteria.

Discovery of new peptide communication factor in bacteria
http://www.news-medical.net/?id=31887
Discovery by Hebrew University of Jerusalem researchers of a new communication factor that enables bacteria to "talk to each other" and causes their death could have significant consequences leading to development of a new class of antibiotic medications.

Step towards vaccine to prevent Chlamydia
http://www.news-medical.net/?id=31882
Genetically engineered mice may hold the key to helping scientists from Queensland University of Technology and Harvard hasten the development of a vaccine to protect adolescent girls against the most common sexually transmitted disease, Chlamydia.

New magnetic separation 'traveling wave magnetophoresis' might detect multiple pathogens at once
http://www.news-medical.net/?id=31886
A magnetic separation technique developed by researchers at Duke University's Pratt School of Engineering and Purdue University makes it relatively simple to sort through beads hundreds of times smaller than the period at the end of this sentence.

Research clarifies origin of mammalian network of lymphatic vessels
http://www.news-medical.net/?id=31901
Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature - the network of vessels and capillaries critical to various essential housekeeping functions in the body.

Researchers show evidence of 'memory' in cells and molecules
http://www.news-medical.net/?id=31898
Research to be reported October 29 in the journal Proceedings of the National Academy of Sciences (PNAS) provides evidence that some molecular interactions on cell surfaces may have a "memory" that affects their future interactions.

UGA researchers create carbohydrate-based cancer vaccine
http://www.news-medical.net/?id=31911
When cells become cancerous, the sugars on their surfaces undergo distinct changes that set them apart from healthy cells.

New insights into how the brain takes in and assembles stimuli from the outside world
http://www.news-medical.net/?id=31900
The area of the brain that processes sounds entering the ears also appears to process stimulus entering the eyes, providing a novel explanation for why many viewers believe that ventriloquists have thrown their voices to the mouths of their dummies.

Epilepsy-induced brain cell damage blocked in lab experiments
http://www.news-medical.net/?id=31876
For some epilepsy patients, the side effects of epilepsy can be as troubling as the seizures.

Hunger influenced by leptin hormone
http://www.news-medical.net/?id=31870
Researchers at UCLA have determined the brain circuits involved in hunger that are influenced by a hormone called leptin.

New egg-specific gene, JY-1 offers clues to infertility
http://www.news-medical.net/?id=31883
A newly identified gene that controls embryo development in cows may someday offer clues into the cause of infertility in women.

Research finds novel mechanism for synovial inflammation in degenerative arthritis
http://www.news-medical.net/?id=31885
The most common degenerative joint disease, osteoarthritis (OA) is marked by the breakdown of articular cartilage, which is the type of cartilage that lines the ends of most limb bones.

Hairpin-shaped mimetics imitate the helical protein that plays a role in the spread of HIV
http://www.news-medical.net/?id=31850
When a host cell is infected with HIV, the virus brings its own genetic material into the host cell. This cell then replicates, reads the viral RNA, and uses it as a blueprint to produce more viral proteins.

One-third of Americans under extreme stress
http://www.news-medical.net/?id=31841
According to the latest survey as many as one-third of American adults is under extreme stress.

Possible biomarker for colon cancer in people 50 and under
http://www.news-medical.net/?id=31811
An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease.

Possible biomarker for colon cancer in people under 50
http://www.news-medical.net/?id=31829
An abnormality of chromosomes long associated with diseases of aging has, for the first time, been linked to colon cancer in people 50 years old and younger, an age group usually considered young for this disease.

Research identifies two genes that may play a role in insulin resistance
http://www.news-medical.net/?id=31826
New research from UAB (University of Alabama at Birmingham) identifies two genes that may play a role in insulin resistance, opening a new avenue for researchers searching for treatments for type 2 diabetes and metabolic syndrome.

Therapeutic gene expression can be sustainable for 1 year
http://www.news-medical.net/?id=31816
Researchers at the Board of Governors Gene Therapeutics Research Institute at Cedars-Sinai Medical Center have shown for the first time that it is possible to sustain therapeutic gene expression in the central nervous system for up to a year, even in the presence of an anti-viral immune response mechanism that is normally present in humans.

Discovery of a key cell-signaling pathway
http://www.news-medical.net/?id=31799
University of Alabama at Birmingham (UAB) researchers have discovered a key cell-signaling pathway that regulates cell progression and switches on front-to-back body patterning in tadpoles.

Intravenous gene therapy protects normal tissue of mice during whole-body radiation
http://www.news-medical.net/?id=31809
Gene therapy administered intravenously could be an effective agent to protect vital organs and tissues from the effects of ionizing radiation in the event of large-scale exposure from a radiological or nuclear bomb, according to an animal study presented today by University of Pittsburgh researchers at the 49th annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) in Los Angeles.

Researchers find new mechanism explaining the promotional effect of H pylori on gastric cancer
http://www.news-medical.net/?id=31806
The formation of a cancer is proven to be a multi-stage, multi-mechanism process by animal and human studies.

Hypertension drugs may prevent Alzheimer's Disease
http://www.news-medical.net/?id=31796
New research is suggesting that some of the drugs commonly used to treat hypertension (high blood pressure) may offer another benefit.

piRNAs play an important role in controlling gene function
http://www.news-medical.net/?id=31780
A study by researchers at the Yale Stem Cell Center for the first time demonstrates that piRNAs, a recently discovered class of tiny RNAs, play an important role in controlling gene function, it was reported this week in Nature.

Emerging cancer therapies and novel targets
http://www.news-medical.net/?id=31785
What are the cancer drugs of tomorrow and how will they be developed? At the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, researchers will present some answers to these and other pressing questions regarding emerging cancer therapeutics.

A new source of islet cells
http://www.news-medical.net/?id=31786
The shortage of islet cells limits the development of islet transplantation. One new approach was reported in the October 21 issue of the World Journal of Gastroenterology because of its great significance in enhancing the output of islet cells.

New insight into how memory is wired in the human brain
http://www.news-medical.net/?id=31778
Recognizing someone's name but forgetting how you met them is all in your head

French clay fights flesh-eating bug
http://www.news-medical.net/?id=31756
French clay that kills several kinds of disease-causing bacteria is at the forefront of new research into age-old, nearly forgotten, but surprisingly potent cures.

New target for Hepatocellular carcinoma therapy
http://www.news-medical.net/?id=31747
Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation.

Researchers discover drug-craving brain region in rats
http://www.news-medical.net/?id=31751
Chilean researchers have identified a region of the brain - the insular cortex - that plays a role in drug craving in amphetamine-addicted rats, according to a report published in the 26 October issue of the journal Science, published by the American Association for the Advancement of Science (AAAS), the nonprofit science society.

How to design a cancer-killing virus
http://www.news-medical.net/?id=31761
One new way to treat individuals with cancer that is being developed is the use of viruses that infect and kill cancer cells while leaving normal cells unharmed.

Stanford researchers get precise picture of cell target for drugs
http://www.news-medical.net/?id=31782
More than half of all drugs given to patients work by targeting a particular type of "docking station," or receptor, found on body cells, to steer the cell's machinery toward healing an illness.

More evidence dopamine plays a role in obesity
http://www.news-medical.net/?id=31758
A brain-imaging study of genetically obese rats conducted at the U.S. Department of Energy's Brookhaven National Laboratory provides more evidence that dopamine - a brain chemical associated with reward, pleasure, movement, and motivation - plays a role in obesity.

Severely restricting calories leads to a longer life
http://www.news-medical.net/?id=31740
New research now has shown for the first time that such a diet also can maintain physical fitness into advanced age, slowing the seemingly inevitable progression to physical disability and loss of independence.

Many medical disorders may be languishing in mountains of discarded gene data
http://www.news-medical.net/?id=31742
Previously hidden obesity-related genes have been uncovered from old experiments by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

Role of cholesteryl ester hydrolase in reducing heart disease identified
http://www.news-medical.net/?id=31737
Virginia Commonwealth University researchers have identified the role of a key enzyme called CEH in reducing heart disease, paving the way for new target therapies to reduce plaques in the arteries and perhaps in the future, help predict a patient's susceptibility to heart disease.

Hands quicker than eyes when it comes to screening
http://www.news-medical.net/?id=31739
That fleeting moment of regret between clicking the wrong icon and seeing an unwanted web page pop onto the screen could make a huge difference in improving the accuracy of visual searches in medicine and homeland security.

Researchers find crucial signal that switches on eye development
http://www.news-medical.net/?id=31734
Researchers at the University of Warwick, funded by Wellcome Trust, have uncovered a crucial signal that switches on eye development.

Sounds can alter how masculine or feminine a person looks
http://www.news-medical.net/?id=31697
Think about the confused feelings that occur when you meet someone whose tone of voice doesn't seem to quite fit with his or her gender.

Potential new ways to treat ulcers
http://www.news-medical.net/?id=31704
The alarming truth is more than 14.5 million people suffer from ulcers worldwide due to factors such as stress and the use of non-steroidal anti-inflammatory drugs (NSAIDS).

Amazon jungle plant compound blocks tissue destruction
http://www.news-medical.net/?id=31710
Scientists at Case Western Reserve University's School of Medicine have published in the Journal of Inflammation a remarkable discovery with a natural product derived from the Amazon rainforest.

Purer medicines
http://www.news-medical.net/?id=31722
Dutch researcher Roelof Mol has investigated possibilities for more accurately determining the composition of medicines.

Canadians would welcome HPV vaccine if it were free
http://www.news-medical.net/?id=31684
Canadians would welcome a vaccine against the human papillomavirus (HPV) if it were introduced at no charge, a Quebec, Canada survey suggests.

Public access policy for NIH-funded research set to become law
http://www.news-medical.net/?id=31708
The U.S. Senate last night approved the FY2008 Labor, HHS, and Education Appropriations Bill (S.1710), including a provision that directs the National Institutes of Health (NIH) to strengthen its Public Access Policy by requiring rather than requesting participation by researchers.

New understanding of vagus nerve's role in regulating inflammation
http://www.news-medical.net/?id=31690
It used to be dogma that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature.

Increased intestinal permeability by exogenous sphingomyelinase
http://www.news-medical.net/?id=31702
Many signaling molecules involved in the pathogenesis of IBD, such as TNF or IFN, infections with bacteria or viruses and ionizing radiation, may cause an alteration of the lipid composition in the cell membrane by activation of sphingomyelinases (SMases).

Researchers discover important tool in understanding differentiation in human embryonic stem cells
http://www.news-medical.net/?id=31733
Researchers at the University of Minnesota's Stem Cell Institute have described how an existing genetic tool can be used to study how human embryonic stem cells differentiate.

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