16 octobre, 2007 08:40
Agent Orange & Birth Defectsand pubmed study. Plus other information on the effects of, Agent Orange
Dow Chemical; created to harm innocent persons and Children. Like Dow's, toxic breast implants cause millions of women; and there Children to become drastically ill. Dow Chemical, has lied and never quits to keep from compensating us, there asbestos victims, Gulf war an Agent Orange Vets.
http://www.agentorangebirthdefects.blogspot.com/
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Australian Vets Win $13.5 Million Study of Child Defects
The Australian Federal Government has announced a decision to commission a $13.5 million, eight-year study into the health of children of Vietnam veterans. The first results of this study will be out in 2009.
The Minister for Veterans' Affairs, Bruce Billson, announced the study this week, to be done by a research institute yet to be chosen.
Vietnam veterans' children have long been thought to be vulnerable to the effects of the defoliant Agent Orange and other health problems. Agent Orange, which includes the deadly compound dioxin, has been suspected of having an effect on human stem cells and thereby on future generations. More see: Veterans win $13.5m child study.
Posted by Birth Defect Research for Children at 5:13 AM 0 comments
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Wednesday, July 18, 2007
Dioxins Associated With Learning and Attention Disorders
Association of serum concentrations of persistent organic pollutants with the prevalence of learning disability and attention deficit disorder.
Department of Preventive Medicine, School of Medicine, Kyungpook University, 101 Dongin-dong, Jung-gu, Daegu 700-422, Korea. lee_dh@knu.ac.kr
OBJECTIVE: Even though persistent organic pollutants (POPs) are well-known neurotoxicants, there is no previous study, even cross-sectional, on the association between background exposure to POPs and clinically significant developmental disorders, such as learning disability (LD) or attention deficit disorder (ADD), among children from a general population. DESIGN: Cross-sectional study. SETTING: Study subjects were 278 children aged 12-15 years included in the National Health and Nutrition Examination Survey 1999-2000. The seven most commonly detected POPs (each detectable in >/=20% of children: 3,3',4,4',5-pentachlorobiphenyl; 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HPCDD); 1,2,3,4,6,7,8,9-octachlorodibenzo-p-dioxin (OCDD); 1,2,3,4,6,7,8-heptachlorodibenzofuran (HPCDF); beta-hexachlorocyclohexane; p,p'-dichlorodiphenyltrichloroethane; and trans-nonachlor) were selected. MAIN RESULTS: Compared with children with non-detectable levels of POPs, adjusted prevalence ORs (95% CIs) of LD among those with detectable levels of HPCDD, OCDD or HPCDF were 2.08 ( 1.17 to 3.68), 2.72 (1.24 to 5.99) and 2.18 (1.15 to 4.15), respectively. For ADD, the corresponding figures were 3.41 (1.08 to 10.8), 3.33 (0.94 to 11.8) and 2.31 (0.62 to 8.63), respectively. CONCLUSIONS: Associations were observed between serum concentrations of POPs belonging to the categories of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans and the prevalence of two clinically significant development problems, LD and ADD. The nature of these associations needs to be clarified by prospective studies.
Posted by Birth Defect Research for Children at 11:21 AM 0 comments
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Thursday, July 12, 2007
Birth Defect Registry Data on Agent Orange
The National Birth Defect Registry sponsored by Birth Defect Research for Children collects data on birth defects and disabilities in the children of Vietnam veterans. To view charts on these cases, go to this slide presentation which was made to the National Institute of Environmental Health Sciences. http://www.birthdefects.org/NIEHS/3510.html To add your child's case to the registry, go to www.birthdefects.org and click on the registry on the home page.
Posted by Birth Defect Research for Children at 6:56 AM 3 comments
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Tuesday, July 10, 2007
Agent Orange plaintiff dies of cancer. One of the key plaintiffs of a group of Vietnamese suing US manufacturers of the war-time defoliant Agent Orange has died only four days after returning from attending an appeal of the case. Bangkok Post, Thailand. 9 July 2007.
Posted by Birth Defect Research for Children at 8:49 AM 0 comments
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Monday, July 2, 200
Agent Orange & Genetic Changes
Free Abstract Article (Fulltext) Article (PDF 112 KB)
Original Article
Elevated sister chromatid exchange frequencies in New Zealand Vietnam War veteransR.E. Rowlanda, L.A. Edwardsa, J.V. PoddbaInstitute of Molecular Biosciences andbSchool of Psychology, Massey University, Palmerston North (New Zealand)
Address of Corresponding Author
Cytogenetic and Genome Research 2007;116:248-251 (DOI: 10.1159/000100407)
http://content.karger.com/produktedb/produkte.asp?typ=fulltext&file=000100407 - OLNAbstract.
From July 1965 until November 1971, New Zealand Defence Force Personnel fought in the Vietnam War. During this time more than 76,500,000 litres of phenoxylic herbicides were sprayed over parts of Southern Vietnam and Laos, the most common being known as 'Agent Orange'. The current study aimed to ascertain whether or not New Zealand Vietnam War veterans show evidence of genetic disturbance arising as a consequence of their now confirmed exposure to these defoliants. A sample group of 24 New Zealand Vietnam War veterans and 23 control volunteers were compared using an SCE (sister chromatid exchange) analysis. The results from the SCE study show a highly significant difference (P < 0.001) between the mean of the experimental group (11.05) and the mean of a matched control group (8.18). The experimental group also has an exceptionally high proportion of HFCs (cells with high SCE frequencies) above the 95th percentile compared to the controls (11.0 and 0.07%, respectively). We conclude that the New Zealand Vietnam War veterans studied here were exposed to a clastogenic substance(s) which continues to exert an observable genetic effect today, and suggest that this is attributable to their service in Vietnam.
Posted by Birth Defect Research for Children at 1:44 PM 9 comments
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Combined Analysis Agent Orange and Birth Defects
: Int J Epidemiol. 2006 Oct;35(5):1220-30. Epub 2006 Mar
16.http://www.ncbi.nlm.nih.gov/entrez/utils/fref.fcgi?PrId=3051&itool=AbstractPlus-def&uid=16543362&db=pubmed&url=http://ije.oxfordjournals.org/cgi/pmidlookup?view=long&pmid=16543362
Links
Comment in:
Int J Epidemiol. 2006 Oct;35(5):1230-2.
Association between Agent Orange and birth defects: systematic review and meta-analysis.
Ngo AD, Taylor R, Roberts CL, Nguyen TV.
School of Public Health, University of Texas Health Science Center, USA.
BACKGROUND: The association between parental exposure to Agent Orange or dioxin and birth defects is controversial, due to inconsistent findings in the literature. The principal aim of this study was to conduct a meta-analysis of relevant epidemiological studies that examined this association and to assess the heterogeneity among studies. METHODS: Relevant studies were identified through a computerized literature search of Medline and Embase from 1966 to 2002; reviewing the reference list of retrieved articles and conference proceedings; and contacting researchers for unpublished studies. A specified protocol was followed to extract data on study details and outcomes. Both fixed-effects and random-effects models were used to synthesize the results of individual studies. The Cochrane Q test and index of heterogeneity (I2) were used to evaluate heterogeneity, and a funnel plot and Egger's test were used to evaluate publication bias. RESULTS: In total, 22 studies including 13 Vietnamese and nine non-Vietnamese studies were identified. The summary relative risk (RR) of birth defects associated with exposure to Agent Orange was 1.95 [95% confidence interval (95% CI) 1.59-2.39], with substantial heterogeneity across studies. Vietnamese studies showed a higher summary RR (RR = 3.00; 95% CI 2.19-4.12) than non-Vietnamese studies (RR = 1.29; 95% CI 1.04-1.59). Sub-group analyses found that the magnitude of association tended to increase with greater degrees of exposure to Agent Orange, rated on intensity and duration of exposure and dioxin concentrations measured in affected populations. CONCLUSION: Parental exposure to Agent Orange appears to be associated with an increased risk of birth defects.
PMID: 16543362 [PubMed - indexed for MEDLINE]
