The Editor at News-Medical.Net <editor@news-medical.net>

Dmp1 gene and lung cancer
http://www.news-medical.net/?id=31251
The first research to show the involvement of a gene known as Dmp1 in human lung cancer will hopefully lead to an increased understanding on what goes wrong at the cellular level to cause the disease, according to researchers from Wake Forest University School of Medicine reporting in Cancer Cell .

Research to investigate the experiences of the black African population in Britain
http://www.news-medical.net/?id=31247
Two researchers at the University of Kent have been awarded £98,924 by the Economic and Social Research Council (ESRC) to investigate the topic Black Africans in Britain: Integration or Segregation.

Counting during anesthetic injection lessens pain
http://www.news-medical.net/?id=31243
Patients who counted aloud during the injection of an intravenous anesthetic experienced and recalled less pain, according to new research by anesthesiologists in Japan.

Researchers specifically manipulate tumor angiogenesis gene
http://www.news-medical.net/?id=31248
Angiogenesis is a common process that is essential for tumor growth beyond 2 mm. Although numerous growth factors are involved, vascular endothelial growth factor (VEGF), particularly VEGF-A, has been shown to play an important role in tumor angiogenesis.

Over 2 decades experiences shows that ultrasound-guided liver biopsy is the procedure of choice
http://www.news-medical.net/?id=31241
Liver biopsy is a widely used tool in the investigation of liver diseases. It is invasive and has a mortality risk ranging between 0.01% and 0.17%. A liver biopsy should therefore only be performed in patients who would potentially benefit from it.

Insomniac fish help understand the genetics behind sleep disorders
http://www.news-medical.net/?id=31235
Scientists at the Stanford University School of Medicine have hooked a fish that suffers from insomnia in their quest to understand the genetics behind sleep disorders.

Garlic... bad on the nose but good on the heart!
http://www.news-medical.net/?id=31233
According to the latest research it is the smelly ingredient in garlic that is good for your health.

Newly solved structure reveals how cells resist oxygen damage
http://www.news-medical.net/?id=31225
The sun's rays give life, but also take it away. Singlet oxygen, a byproduct of the photosynthetic process by which certain cells convert sunlight into energy, is a highly toxic and reactive substance that tears cells apart.

Delisheng shows anti-cancer effects on hepatocellular carcinoma
http://www.news-medical.net/?id=31183
Traditional Chinese medicine is world renowned. It has supernatural effects on some diseases, but the reason is still unknown. One such article was recently reported in the November 7 issue of the World Journal of Gastroenterology dealing with the great significance of a Chinese medicinal compound, "delisheng", for the therapy of HCC and its neoteric research method.

Researchers working on the development of drugs to limit neuronal death
http://www.news-medical.net/?id=31212
Neurons die en masse when the spinal cord is injured or when a person suffers a stroke. Researchers of the Max Delbrueck Center for Molecular Medicine (MDC) Berlin-Buch, Germany, and of Aarhus University, Denmark, have unraveled the molecular mechanism which causes the death not only of damaged neurons, but also of healthy nerve cells.

New active compound for the treatment of malaria
http://www.news-medical.net/?id=31218
Malaria is caused by Plasmodium parasites and it is the female Anopheles mosquito that acts as a vector for these malarial parasites in to the human body.

Homocysteine appears to be play a part in retinal damage and vision loss
http://www.news-medical.net/?id=31209
Homocysteine, an amino acid believed to contribute to heart attack, stroke and dementia, likely also is a player in retinal damage and vision loss, researchers say.

Enhanced DNA-repair mechanism can cause breast cancer
http://www.news-medical.net/?id=31200
Although defects in the "breast cancer gene," BRCA1, have been known for years to increase the risk for breast cancer, exactly how it can lead to tumor growth has remained a mystery.

Agency for Healthcare Research and Quality expands research on therapeutics program
http://www.news-medical.net/?id=31186
The Agency for Healthcare Research and Quality, part of the U.S. Department of Health and Human Services, announced the award of $41.6 million over the next 4 years for a new coordinating center and 10 research centers as part of its Centers for Education and Research on Therapeutics (CERTs) program.

New near-infrared contrast agent reveals bone and breast-cancer-related microcalcifications
http://www.news-medical.net/?id=31179
Mammography continues to be the method of choice for the early detection of breast cancer. However, because this technique is not as selective or specific as one would wish, and does not deliver reliable results for every level of tissue density, alternatives are being sought.

Animal food allergens unmasked
http://www.news-medical.net/?id=31135
The relatedness of an animal food protein to a human protein determines whether it can cause allergy, according to new research by scientists from the Institute of Food Research in Norwich and the Medical University of Vienna.

New gene findings show that controls of lifespan and cancer have deep, common roots
http://www.news-medical.net/?id=31152
A person is 100 times more likely to get cancer at age 65 than at age 35. But new research reported in the journal "Nature Genetics" identifies naturally occurring processes that allow many genes to both slow aging and protect against cancer in the much-studied C. elegans roundworm.

3-D model of the mammary gland reveals secrets of cancer cells
http://www.news-medical.net/?id=31175
A trans-Atlantic tie up between scientists at the University of Ulster and the Tufts University School of Medicine in Boston could lead to a greater understanding of the triggers that affect cancer cells.

Hooked on chocolate? the answer why may lie in your gut
http://www.news-medical.net/?id=31172
For the first time, scientists have linked the all-too-human preference for a food - chocolate - to a specific, chemical signature that may be programmed into the metabolic system and is detectable by laboratory tests.

The importance of the endocannabinoid-system
http://www.news-medical.net/?id=31174
Cannabis (marijuana) is the most widely produced plant-based illicit drug worldwide and the illegal drug most frequently used in Europe.

Six years advance warning of Alzheimer's
http://www.news-medical.net/?id=31137
One of the most distressing aspects of Alzheimer's disease is the difficulty in determining whether mild memory problems are the beginning of an inevitable mental decline.

People with lower dopamine levels eat more
http://www.news-medical.net/?id=31151
Science has found one likely contributor to the way that some folks eat to live and others live to eat.

How does the opioid system work?
http://www.news-medical.net/?id=31153
The opioid system controls pain, reward and addictive behaviors. Opioids exert their pharmacological actions through three opioid receptors, mu, delta and kappa whose genes have been cloned (Oprm, Oprd1 and Oprk1, respectively).

Scientists identify brain circuits that 'decide' how much we eat
http://www.news-medical.net/?id=31132
Scientists have identified the brain circuits that 'decide' how much we eat. Using live brain scanning techniques and an innovative study design, researchers have discovered how the brain controls food intake in humans. Their findings are published in Nature.

New molecules discovered that block cancer cells from modifying cell DNA
http://www.news-medical.net/?id=31101
Researchers have discovered new small molecules that may prevent prostate cancer cells from turning off normal genes in a process that transforms normal cells into cancer cells. This significant discovery in the field of epigenetics has immediate implications in the development of new diagnostic tests and cancer medications.

New rapid and accurate method to identify adenoviruses
http://www.news-medical.net/?id=31113
Grantees of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have adapted a rapid and accurate new molecular typing strategy and used it to conduct one of the most comprehensive studies of adenoviruses ever performed in the United States.

Researchers focus on neuregulin gene and schizophrenia
http://www.news-medical.net/?id=31116
Queen's scientists have started research on a human gene that will lead to a better understanding of schizophrenia.

Picking the right stress test for heart disease risk analysis
http://www.news-medical.net/?id=31123
Stress tests are good front-line tests indicators of heart disease, but just how good depends on ordering the right one, researchers say.

New research may show why some prostate cancer recurs after treatment
http://www.news-medical.net/?id=31102
Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth.

Transthyretin protein may accelerate atherosclerosis
http://www.news-medical.net/?id=31120
Scientists report in the November 2007 issue of the Journal of Lipid Research that a protein called transthyretin (TTR) that is present in the blood may accelerate the development of atherosclerosis - a potentially fatal heart disease in which the arteries are progressively narrowed and hardened over time, reducing blood flow to the heart.

A tumor-blocking protein may be key in developing deadly form of pancreatic cancer
http://www.news-medical.net/?id=31095
A tumor-blocking protein previously implicated in prostate and breast cancer development may also be behind the most aggressive type of pancreatic cancer. Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have discovered that the protein pp32 - which normally applies the brakes on a cancer-causing gene - is missing in an aggressive form of pancreatic cancer.

Red wines may defend against food-borne pathogens
http://www.news-medical.net/?id=31114
Red wine is known to have multiple health benefits. Researchers at the University of Missouri-Columbia have found that red wine may also protect humans from common food-borne diseases.

Discovery of protein that plays a key role in the recycling of iron from blood
http://www.news-medical.net/?id=31099
Scientists working in the only lab at MIT doing hematology research have uncovered a protein that plays a key role in the recycling of iron from blood. Their work, described in the October 11 Journal of Clinical Investigation, could lead to new therapies for certain inherited blood disorders such as beta-thalassemia, a condition that causes chronic anemia.

Penn awarded $2.1 million grant for cardiovascular research
http://www.news-medical.net/?id=31106
Cardiac researchers at the University of Pennsylvania have received a $2.1 million grant from the National Institutes of Health (NIH) to pioneer studies in cardiovascular disease management and participate in a novel collaboration network to develop and implement research in this critically important field.

RNA-binding protein key to understanding myotonic dystrophy type 1
http://www.news-medical.net/?id=31118
Increased levels of a protein called CUGBP1 play an important role in the adult-onset form of muscular dystrophy called myotonic dystrophy type 1, said Baylor College of Medicine researchers in a report that appears in the journal Molecular Cell.

Statins cut heart attacks by more than a quarter
http://www.news-medical.net/?id=31124
A study into the use of cholesterol-lowering drugs has found they reduce heart attacks by more than 25 per cent.

Gene SIRT1 could lead to new cholesterol strategies
http://www.news-medical.net/?id=31098
MIT researchers have discovered a link between a gene believed to promote long lifespan and a pathway that flushes cholesterol from the body. The finding could help researchers create drugs that lower the risk of diseases associated with high cholesterol, including atherosclerosis (clogged arteries) and Alzheimer's disease.

Analysis of breast and colon cancer genes finds 5,000 previously unmapped genes
http://www.news-medical.net/?id=31081
Researchers from University Hospitals (UH) Ireland Cancer Center and Case Western Reserve University School of Medicine are part of a new national study that has analyzed more than 18,000 genes, including 5,000 previously unmapped genes, from breast and colorectal tumors.

Genome update defines landscape of breast and colon cancers
http://www.news-medical.net/?id=31091
One year after completing the first large-scale report sequencing breast and colon cancer genes, Johns Hopkins Kimmel Cancer Center scientists have studied the vast majority of protein-coding genes which now suggest a landscape dominated by genes that each are mutated in relatively few cancers.

Compound called apolipoprotein B in blood better at predicting coronary heart disease in Chinese people
http://www.news-medical.net/?id=31093
Scientists report in the November 2007 issue of the Journal of Lipid Research that the concentration of a compound called apolipoprotein B in the blood is better at predicting whether Chinese have coronary heart disease - in which fatty deposits clog arteries that supply blood and oxygen to the heart - than other substances such as blood cholesterol levels.

New understanding of stem cell aging
http://www.news-medical.net/?id=31067
The Stowers Institute's Xie Lab has published recent findings that reveal some of the factors underlying the aging of stem cells.

Cancer researchers investigate free radicals
http://www.news-medical.net/?id=31073
The University of Leicester has been selected as the hub of a worldwide network of researchers to investigate one of the causes of cancer.

Behavior of drug-dependent offenders
http://www.news-medical.net/?id=31057
Researchers at the University of Leicester have worked with Northamptonshire Police's Scientific Support Unit to research whether or not drug-dependent offenders were more likely to be apprehended through forensic science techniques than those who were not.

Better understanding of environmental influences on the aging process of stem cells
http://www.news-medical.net/?id=31053
A stem cells' immediate neighborhood, a specialized environment also known as the stem cell niche, provides crucial support needed for stem cell maintenance.

Obese people six times more likely to develop oesophageal cancer
http://www.news-medical.net/?id=31055
Rates of oesophageal cancer have been rising rapidly, and in some countries, they have risen faster than those of every other major cancer, say the authors.

Research shows how stem cells decide to become either skeletal or smooth muscle
http://www.news-medical.net/?id=31068
Researchers have discovered a key protein that controls how stem cells "choose" to become either skeletal muscle cells that move limbs, or smooth muscle cells that support blood vessels, according to a study published in the Proceedings of the National Academy of Sciences (PNAS).

Brookhaven's D-peptides halt HIV entry into cells
http://www.news-medical.net/?id=31058
Based in part on protein structures determined at the National Synchrotron Light Source (NSLS) at the U.S. Department of Energy's Brookhaven National Laboratory, scientists at the University of Utah have developed new peptides that appear to be significantly more effective at blocking HIV's entry into cells than other drugs in their class.

Immune system protein shows potential as early warning system for lung cancer
http://www.news-medical.net/?id=31059
An immune system protein could act as an early warning system for lung cancer, reveals research published ahead of print in the journal Thorax.

Bacteria reveal targets of immune responses quick and direct identification of antigens
http://www.news-medical.net/?id=31037
The Epstein-Barr virus (EBV) is a widespread herpes virus that infects more than 90 per cent of the worldwide human population.

Adult stem cells lack key pluripotency regulator
http://www.news-medical.net/?id=31034
The protein Oct4 plays a major role in embryonic stem cells, acting as a master regulator of the genes that keep the cells in an undifferentiated state.

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