Myrl Jeffcoat wisgroup_leader@yahoo.com

Thanks to Pam Dowd for sending the following. . .Myrl

While Dow Corning has been out of the public implant business, their scientists are still in the game.

Silicone Gel Breast Implant Rupture Rates: Research Issues.

Annals of Plastic Surgery. 48(1):92-101, January 2002.

Abstract:
Documenting the rate of rupture of silicone breast implants appears to be deceptively easy. Largely because of the phenomenon of "silent rupture," it isn't. The authors explore the various technical biases (selection, misclassification, and confounding) and methodological problems that have plagued much of the research conducted to date. By means of a series of illustrations, they argue that explantation has limited utility. Noninvasive techniques have to be used to gather the proper type of data on the timing and frequency of these events. Only with the proper incidence data will researchers be able to identify better the different mechanisms underlying implant rupture and the relative importance of each. The authors recommend that better and standardized definitions of implant rupture be developed, that greater recognition be given to the technical biases and a greater effort be made to eliminate them from investigations of implant rupture, and that more research be conducted by multidisciplinary teams. Because of the growing awareness of the complexity of this issue, the authors also recommend that properly constituted advisory teams be used to provide comprehensive oversight of future research projects from beginning to end.

(C) 2002 Lippincott Williams & Wilkins, Inc.