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The Editor at News-Medical.Net editor@news-medical.net

13 janvier, 2008 17:59

Medical Studies-Trials News Update from News-Medical.Net - 13th January 2008

Ringing in the ears
http://www.news-medical.net/?id=34252
Do your ears ring after a loud concert? Nerves that sense touch in your face and neck may be behind the racket in your brain, University of Michigan researchers say.


Severe and morbid obesity affects chances of kidney transplantation
http://www.news-medical.net/?id=34240
For patients on the waiting list for a kidney transplant, severe and morbid obesity are associated with a lower chance of receiving an organ, reports a study in the February Journal of the American Society of Nephrology.


Comprehensive assessment of long-term effects of reducing intake of energy
http://www.news-medical.net/?id=34237
Overweight people who lose a moderate amount of weight get an immediate benefit in the form of better heart health, according to a study conducted at Washington University School of Medicine in St. Louis.


Review of Memantine for Alzheimer's
http://www.news-medical.net/?id=34245
In a study published this month in the Journal of Alzheimer's Disease, researchers from the University of Aberdeen report that the drug memantine, used for the treatment of Alzheimer's disease and praised as "the first and only representative of a new class of Alzheimer drugs" works in fact similar to other existing compounds, and is beneficial only in a narrow concentration range.


Chemical first found on Easter Island could treat tuberous sclerosis
http://www.news-medical.net/?id=34241
A new study has shown promising results in fighting a severe genetic disorder which can create tumours throughout the body.


Genetic evolution of tumours according to their growth dynamics.
http://www.news-medical.net/?id=34242
A study co-directed by the Universidad Complutense de Madrid and La Paz hospital in Madrid identifies a protein of high expression in cells located at the tumour boundary that could play an essential role in the evolution of tumours and their invasive potential.


Does cholesterol have any benefits?
http://www.news-medical.net/?id=34217
If you're worried about high cholesterol levels and keeping heart-healthy as you get older, don't push aside bacon and eggs just yet. A new study says they might actually provide a benefit.


Chemicals in red wine grapes may prevent tooth decay
http://www.news-medical.net/?id=34223
A class of chemicals in red wine grapes may significantly reduce the ability of bacteria to cause cavities, according to a study published recently in the Journal of Agricultural and Food Chemistry


The drug sirolimus shrinks tumors, improves lung function
http://www.news-medical.net/?id=34219
The drug sirolimus, normally used to help transplant patients fight organ rejection, may eventually be used as a less invasive treatment for a tumor called angiomyolipomata in patients with who would otherwise face surgery.


Uses of medications in psychoanalysis
http://www.news-medical.net/?id=34222
As Americans increasingly seek a "quick fix" to physical and mental ailments, psychoanalysts can be caught in the crossfire of a debate about the potential benefits and drawbacks of including medication in their treatment plans.


Treating venous leg ulcers with honey dressings unlikely to help healing
http://www.news-medical.net/?id=34220
When compared with normal care, treating a leg ulcer with dressings impregnated with honey did not significantly improve the rate of healing, but did lead to a significantly increased number of reported adverse events, according to research published today in the British Journal of Surgery.


Methadone and rare ventricular arrhythmia link
http://www.news-medical.net/?id=34201
Methadone is a possible cause of sudden cardiac death even when it isn't overdosed but is taken at therapeutic levels primarily for relief of chronic pain or drug addiction withdrawal, a new study by Oregon Health & Science University researchers suggests.


Trichloroethylene exposure linked to Parkinsonism
http://www.news-medical.net/?id=34215
Industrial workers who worked with trichloroethylene (TCE) may face a greater risk for parkinsonism, a study by a team of University of Kentucky researchers shows.


Potential new treatments for Huntington's disease
http://www.news-medical.net/?id=34216
Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington's disease causes neurodegeneration.


Investigational treatment for advanced melanoma to be studied
http://www.news-medical.net/?id=34221
University of Illinois at Chicago researchers are participating in a multi-center research trial to evaluate the safety and effectiveness of Allovectin-7, an investigational treatment for advanced melanoma.


New study highlights importance soluble proteins, called cytokines, in Alzheimer's
http://www.news-medical.net/?id=34210
An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer's disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation .


Sixty percent of psychotherapy clients felt therapy didn't end on time
http://www.news-medical.net/?id=34179
Sixty percent of private practice dynamically oriented psychotherapy clients felt that their therapy either lasted too long or ended too soon, according to recent research conducted by Prof. David Roe, Head of the Department of Community Mental Health, Faculty of Social Welfare and Health Sciences at the University of Haifa.


New insight into the mechanisms underlying amnesia
http://www.news-medical.net/?id=34197
Brain scans of hypnotized people that are taken as they forget and are triggered to remember have revealed neural circuitry that is key to the memory suppression and recall process.


Eating out can have both positive and negative impact on obesity
http://www.news-medical.net/?id=34188
Eating out instead of cooking at home continues to increase as a factor impacting the American diet. Americans face a large variety of food options and food establishments when choosing to eat out.


Overweight people may not know when they've had enough
http://www.news-medical.net/?id=34207
Researchers at the U.S. Department of Energy's Brookhaven National Laboratory have found new clues to why some people overeat and gain weight while others don't.


Drug deferoxamine boosts bone healing and re-growth
http://www.news-medical.net/?id=34204
A drug originally used to treat iron poisoning can significantly boost the body's own ability to heal and re-grow injured bones, according to researchers at the University of Alabama at Birmingham (UAB).


Acrylamide is carcinogenic and may increase the risk of breast cancer
http://www.news-medical.net/?id=34178
Acrylamide is a chemical formed when frying, roasting, grilling or baking carbohydrate-rich foods at temperatures above 120°C.


Living with nut allergies
http://www.news-medical.net/?id=34200
The incidence of nut allergy is on the increase in Western societies, as is the attention it receives from the public and from the media, yet little research has been carried out on the impact of living with the condition.


Divorce may hinder father-child closeness
http://www.news-medical.net/?id=34187
The typical distancing from parents by adolescents is exacerbated by divorce for fathers, but not for mothers, according to a recent study published in the Journal of Marriage and Family.


Newer meningitis vaccine MenACWY appears safe and effective for infants
http://www.news-medical.net/?id=34132
A vaccine not yet licensed in the United States produces immunity against four strains of meningococcal disease and is well tolerated when administered to infants, according to a study in the January 9/16 issue of JAMA.


Moderate drinking and exercise key to a longer life
http://www.news-medical.net/?id=34145
People who drink moderate amounts of alcohol and are physically active have a lower risk of death from heart disease and other causes than people who don't drink at all, according to new research.


Trius Therapeutics starts U.S. phase I trial for Oxazolidinone antibacterial drug
http://www.news-medical.net/?id=34149
Trius Therapeutics, Inc. has announced that it initiated its first Phase 1 clinical trial of TR-701, an antibacterial drug candidate intended for treatment of patients with serious Gram-positive bacterial infections, including those caused by MRSA and other drug-resistant strains.


Stimulating the appetite can lead to unrelated impulse purchases
http://www.news-medical.net/?id=34146
Exposure to something that whets the appetite, such as a picture of a mouthwatering dessert, can make a person more impulsive with unrelated purchases, finds a study from the February 2008 issue of the Journal of Consumer Research.


Teens find the benefits of sexual abstinence decline with age
http://www.news-medical.net/?id=34148
The percentage of teens who report solely positive benefits from not having sex declines precipitously with age, according to a new study by scientists at the University of California, San Francisco.


New method for presenting clinical trial survival data
http://www.news-medical.net/?id=34128
Researchers have developed a new method for presenting clinical trial survival data that includes data from all trial participants unlike the standard method, according to a commentary published online January 8 in the Journal of the National Cancer Institute.


Drug metformin and lifestyle changes can help treat weight gain induced by antipsychotic drugs
http://www.news-medical.net/?id=34112
Lifestyle intervention and the drug metformin are both effective against antipsychotic-induced weight gain, and treatment is most effective when the two therapies are combined, according to a study in the January 9/16 issue of JAMA.


Carrot cake study on sugar in type 2 diabetes
http://www.news-medical.net/?id=34108
Patients with type 2 diabetes are often advised to cut out sucrose (table sugar) all together.


Multiple behavioral risks for skin cancer among U.S. adults
http://www.news-medical.net/?id=34125
Whether you're basking on the beach during vacation, coasting down glittering white snow on a weekend ski trip, or simply walking the dog or running errands, sunlight's ultraviolet rays can damage your skin year-round.


Oatmeal and cholesterol reduction
http://www.news-medical.net/?id=34135
A new scientific review of the most current research shows the link between eating oatmeal and cholesterol reduction to be stronger than when the FDA initially approved the health claim's appearance on food labels in 1997.


Maintaining a strict diet - study looks at boredom
http://www.news-medical.net/?id=34150
Repetition usually makes people enjoy things less. Such satiation causes our favorites to lose their sheen, makes it hard to follow a diet, and pushes us to escalate our spending on novelty. Life has even been called a "hedonic treadmill" where we must find better and better experiences just to stay happy.


Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
http://www.news-medical.net/?id=34119
Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk.


Americans pay the most for prescription drugs and still don't take them
http://www.news-medical.net/?id=34102
An international study of dialysis patients shows that although U.S. residents have the highest out-of-pocket drug costs, even those who can afford their prescription drugs are far less likely to take them than patients in other countries.


Freeze-dried tendon grafts loaded with gene therapy may provide repair injured tendons
http://www.news-medical.net/?id=34118
According to study data published today in the journal Molecular Therapy, a new graft technique may provide the first effective framework around which flexor tendon tissue can reorganize as it heals.


Taranabant shows promise for weight loss in obese people
http://www.news-medical.net/?id=34115
The first clinical studies of an experimental drug have revealed that obese people who take it for 12 weeks lose weight, even at very low doses.


Higher Medicare spending yields mixed bag for patients
http://www.news-medical.net/?id=34121
Many recent studies have found that Medicare spending across the country varies greatly.


Docetaxel given after doxorubicin reduces recurrence
http://www.news-medical.net/?id=34113
Adding the drug docetaxel to anthracycline-based chemotherapy slightly improved disease-free survival in breast cancer patients, according to a randomized clinical trial published online January 8 in the Journal of the National Cancer Institute.


Heavy smokers most likely to turn to treatment
http://www.news-medical.net/?id=34120
Smokers who seek out treatment to give up the habit are less successful at quitting than smokers who try to snuff the habit without help, according to a new study.


Study proves the co-pay connection in chronic disease
http://www.news-medical.net/?id=34147
As 2008 begins, millions of Americans are having to dig deeper into their own pockets every time they refill a prescription or see a doctor.


Heartening news for tipplers - moderate drinking plus exercise the key to a long life!
http://www.news-medical.net/?id=34166
The latest research is adding to the growing body of evidence which suggests that moderate amounts of alcohol offer health benefits.


Four golden rules can give you 14 extra years of life
http://www.news-medical.net/?id=34161
According to scientists in Britain there are four golden rules to living a longer healthier life and they say people who take them onboard live on average for another fourteen years.


Lack of imagination in older adults linked to declining memory
http://www.news-medical.net/?id=34071
Most children are able to imagine their future selves as astronauts, politicians or even superheroes; however, many older adults find it difficult to recollect past events, let alone generate new ones.


Rockefeller University funds clinical, translational pilot studies
http://www.news-medical.net/?id=34087
The Rockefeller University Center for Clinical and Translational Science (CCTS) has announced the recipients of its 2008 Pilot Project grants.


Increased exposure to sunlight may be good for some people
http://www.news-medical.net/?id=34076
A new study by scientists at the U.S. Department of Energy's Brookhaven National Laboratory and colleagues in Norway suggests that the benefits of moderately increased exposure to sunlight - namely the production of vitamin D, which protects against the lethal effects of many forms of cancer and other diseases - may outweigh the risk of developing skin cancer in populations deficient in vitamin D.


Short periods of stress help condition heart to survive major attack
http://www.news-medical.net/?id=34075
People who experience brief periods of blocked blood flow may be better conditioned to survive a full-blown heart attack later, according to new research from the University of Cincinnati (UC).


Racial disparities in cancer therapy still widespread
http://www.news-medical.net/?id=34057
Black patients are significantly less likely than their white counterparts to receive therapy for various kinds of cancer, despite recent efforts to close gaps in treatment, according to a study by researchers at Yale School of Medicine published in the January 7 online issue of the journal Cancer.


Daytime 'Nanna naps' improve memory
http://www.news-medical.net/?id=34056
A ninety minute daytime nap helps speed up the process of long term memory consolidation, a recent study conducted by Prof. Avi Karni and Dr. Maria Korman of the Center for Brain and Behavior Research at the University of Haifa found.


Congestive heart failure leads to greater disability, nursing home admissions
http://www.news-medical.net/?id=34055
Medical breakthroughs in recent decades have allowed heart attack survivors and other heart-disease patients to live longer.


Vitamin D deficiency linked to increased risk of cardiovascular disease
http://www.news-medical.net/?id=34072
The same vitamin D deficiency that can result in weak bones now has been associated with an increased risk of cardiovascular disease, Framingham Heart Study researchers report in Circulation: Journal of the American Heart Association.


Genital mycoplasmas are a frequent cause of congenital fetal infection
http://www.news-medical.net/?id=34047
Premature babies are subject to a host of threats that can result in fetal/neonatal disease.


Physical education and active play help teens maintain normal weight as adults
http://www.news-medical.net/?id=34081
Adolescents who participate in physical education at school are more likely to maintain a normal weight as young adults, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health.


Scientists can predict psychotic illness in up to 80 percent of high-risk youth
http://www.news-medical.net/?id=34088
Youth who are going to develop psychosis can be identified before their illness becomes full-blown 35 percent of the time if they meet widely accepted criteria for risk, but that figure rises to 65 to 80 percent if they have certain combinations of risk factors, the largest study of its kind has shown.


Girls who eat with their families at mealtimes avoid eating disorders
http://www.news-medical.net/?id=34062
A new study has found that teenage girls who eat meals with their families are more likely to avoid eating disorders such as bulimia.


Controversy over autism and childhood vaccines settled once and for all
http://www.news-medical.net/?id=34043
The results of a new study into the link between childhood vaccines and autism may settle once and for all the controversy over the issue.


Congestive heart failure leads to greater disability among older adults
http://www.news-medical.net/?id=34039
Medical breakthroughs in recent decades have allowed heart attack survivors and other heart-disease patients to live longer. But as their hearts decline into congestive heart failure, an increasing number will experience disability and the need for nursing-home care.


Generation Y complacent about risk of melanoma
http://www.news-medical.net/?id=34038
Generation Y is becoming more complacent about the risk of melanoma and other types of skin cancer, according to a University of New South Wales (UNSW) researcher.


New biomarker for predicting liver cancer spread and survival discovered
http://www.news-medical.net/?id=34036
New research has shown that a unique pattern of microRNAs, small RNA molecules that regulate gene activity, can accurately predict whether liver cancer will spread and whether liver cancer patients will have shorter or longer survival, even patients with early stage disease.


Rib-X Pharmaceuticals initiates two separate Phase II clinical trials for antibiotic compound
http://www.news-medical.net/?id=34017
Rib-X Pharmaceuticals, Inc. has announced the enrolment of the first patients in two separate Phase 2 clinical trials.


Study looks at newly homeless youth and sexual behaviors
http://www.news-medical.net/?id=34020
Newly homeless youth are likelier to engage in risky sexual behavior if they stay in nonfamily settings — such as friends' homes, abandoned buildings or the streets — because they lack supervision and social support, a new UCLA AIDS Institute study has found.


Strength training of neck muscles relieves chronic pain
http://www.news-medical.net/?id=34018
Neck pain has been steadily increasing over the past two decades and is now second to back pain, the most common musculoskeletal disorder.


Minorities less likely to receive pain-relieving opioid drugs in ER
http://www.news-medical.net/?id=34011
Blacks and Hispanics who go to hospital emergency departments in pain are significantly less likely than whites to get pain-relieving opioid drugs, according to a new study funded by the U.S. Department of Health and Human Services.


Exercise improves symptoms of arthritis
http://www.news-medical.net/?id=34000
Patients with arthritis, the country's leading cause of disability, tend to be less fit than their peers who don't have this condition.


Older women heart patients benefit from educational programs - lead to better health
http://www.news-medical.net/?id=34004
Older women heart patients benefit from educational programs as a supplement to clinical care to help significantly lower cardiac symptoms, lose weight and increase physical activity, a new study shows.


Treating children with severe pneumonia at home is just as effective as treating them in hospitals
http://www.news-medical.net/?id=34005
The study results could significantly change the way the illness is managed in developing countries, saving a significant number of lives every year and taking pressure off health systems.


Genmab announces HuMax-CD32b pre-clinical program
http://www.news-medical.net/?id=34002
Genmab A/S has announced a new pre-clinical antibody program called HuMax-CD32b. This fully human IgG1,k antibody targets the CD32b receptor found on immune cells and hematological tumors.


People whose index finger is shorter than their ring finger are at higher risk of osteoarthritis
http://www.news-medical.net/?id=34015
A study of more than 2,000 people, published in the journal Arthritis and Rheumatism, suggests that people whose index finger is shorter than their ring finger are up to twice as likely to suffer from the condition, which is the most common form of arthritis.


Everyone carries at least 1 type of pesticide
http://www.news-medical.net/?id=33995
A study carried out by researchers from the Department of Radiology and Physical Medicine of the University of Granada, in collaboration with the Andalusian School of Public Health (Escuela Andaluza de Salud Publica), found that 100% of Spaniards analyzed had at least one kind of persistent organic compound (POC's), substances internationally classified as potentially harmful to one's health, in their bodies.


Racial disparities persist in cancer care
http://www.news-medical.net/?id=34033
A new study finds that, despite efforts in the last decade to mitigate cancer treatment disparities, black patients are significantly less likely than white patients to receive therapy for various types of cancer.


Pollution from heavy traffic affects the size of an unborn baby
http://www.news-medical.net/?id=34032
According to Australian researchers the pollution caused by heavy traffic affects the size of an unborn baby.


Chances of surviving a heart attack better in an airport or casino than in a U.S. hospital
http://www.news-medical.net/?id=34031
According to the latest research from the United States you have a better chance of surviving a heart attack if you have it in an airport or a casino, rather than a hospital.


Treatment with N-acetylcysteine is associated with better outcomes for children with liver failure
http://www.news-medical.net/?id=33981
A new retrospective study on the effects of N-acetylcysteine (NAC) on children with acute liver failure not caused by acetaminophen poisoning has found that the treatment was associated with a shorter hospital stay, higher incidence of liver recovery, and better survival after transplantation.


Pregnant women who are overweight/obese set the stage for offspring's obesity risk
http://www.news-medical.net/?id=33967
The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants -- individuals under 11 months old -- is alarming.


Study shows how climate change will increase human mortality
http://www.news-medical.net/?id=33956
A Stanford scientist has spelled out for the first time the direct links between increased levels of carbon dioxide in the atmosphere and increases in human mortality, using a state-of-the-art computer model of the atmosphere that incorporates scores of physical and chemical environmental processes.


Peptide hormone found in the body prevents obesity and diabetes
http://www.news-medical.net/?id=33960
A new study finds that a chemical found in the body is capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model.


Magnetic therapy shown to significantly reduce swelling after tissue trauma
http://www.news-medical.net/?id=33966
A recent study by University of Virginia researchers demonstrates that the use of an acute, localized static magnetic field of moderate strength can result in significant reduction of swelling when applied immediately after an inflammatory injury.


Daily alcohol use causes changes in sexual behavior
http://www.news-medical.net/?id=33949
A team of researchers at Penn Sate has used an animal model to reveal, for the first time, a physiological basis for the effect of alcohol on male sexual behavior, including increased sexual arousal and decreased sexual inhibition.


Need for greater recognition of the use of placebos
http://www.news-medical.net/?id=33964
In the first study examining American physicians' use of placebos in clinical practice in the 21st Century, 45 percent of Chicago internists report they have used a placebo at some time during their clinical practice researchers report in the January issue of Journal of General Internal Medicine.


Bright light therapy helps some with bipolar depression
http://www.news-medical.net/?id=33942
Bright light therapy can ease bipolar depression in some patients, according to a study published in the journal Bipolar Disorders.


Upper airway surgery should not be first line treatment for obstructive sleep apnoea in adults
http://www.news-medical.net/?id=33978
Surgery for obstructive sleep apnoea has no clear benefit and should not be offered as a first treatment, argue researchers in this week's BMJ.


$11.3 million autism study launched
http://www.news-medical.net/?id=33955
Autism researchers at the University of Washington will take the initial step in attempting to prevent the developmental disorder when they launch an $11.3 million study this week.


Drinking games and themed parties associated with higher levels of drinking at college
http://www.news-medical.net/?id=33963
Most studies of college-student drinking have looked at the individual, and have relied on self reports. New findings gathered from on-the-spot observations show that parties with drinking games can predict higher blood-alcohol concentrations (BrACs). Young women at theme parties, especially with sexualized themes and costumes, drink more heavily than men.


Treating depression may help alcoholics recover
http://www.news-medical.net/?id=33941
It's hard to stay on the wagon when you're depressed, according to a new study of problem drinkers.


Carnegie Mellon study identifies where thoughts of familiar objects occur inside the human brain
http://www.news-medical.net/?id=33945
A team of Carnegie Mellon University computer scientists and cognitive neuroscientists, combining methods of machine learning and brain imaging, have found a way to identify where people's thoughts and perceptions of familiar objects originate in the brain by identifying the patterns of brain activity associated with the objects.


The dopamine transporter gene influences alcohol withdrawal seizures
http://www.news-medical.net/?id=33979
The physiological component of alcoholism is defined by tolerance and/or withdrawal: the more severe the dependency on alcohol, the more severe the clinical complications, such as greater intensity and/or complications of alcohol withdrawal.


Placebo better than antipsychotic drugs for treating aggression in the intellectually disabled
http://www.news-medical.net/?id=33990
Antipsychotic drugs which are commonly used to treat aggression in people who are intellectually disabled have been revealed to be ineffective.


Surprising number of doctors prescribe placebos
http://www.news-medical.net/?id=33989
The revelation that doctors in the U.S. commonly prescribe placebos has surprised many.


Polyphenols in wine may help prevent cavities
http://www.news-medical.net/?id=33930
A class of chemicals in red wine grapes may significantly reduce the ability of bacteria to cause cavities, according to a study published recently in the Journal of Agricultural and Food Chemistry.


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