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PUTTING BREAKING MEDICAL NEWS INTO PRACTICE^™

Wednesday February 27, 2008

TODAY'S HEADLINES
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For the latest news, features, columns, video and audio reports and more, visit our home page at www.medpagetoday.com

Anemia Drugs Hike Risk of VTE and Death in Cancer Patients

CHICAGO -- Cancer patients who are treated with erythropoietin (Epogen, Procrit) or darbepoetin (Aranesp) for chemotherapy-associated anemia had a 57% increase in risk of venous thromboembolism and a 10% increase in mortality. full story

http://www.medpagetoday.com/HematologyOncology/Chemotherapy/dh/8511

Pfizer Yanks Jarvik Atorvastatin (Lipitor) Ads After Congressional Inquiry
WASHINGTON -- Pfizer said today that it was pulling the plug on advertising that features Robert Jarvik, M.D., promoting the benefit of atorvastatin (Lipitor). full story

http://www.medpagetoday.com/ProductAlert/Prescriptions/dh/8495

Survey What Should the FDA Do About Reprint Marketing?

The FDA has issued draft guidelines that would permit marketing of FDA-approved drugs via scientific reprints that discuss unapproved indications -- currently a forbidden practice. Vote

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Five SSRIs Endorsed as Effective for Obsessive Compulsive Disorder

LONDON -- Five antidepressants given for obsessive compulsive disorder all seem to confer twice the likelihood of modest symptom relief compared with placebo, found a systematic review. full story

http://www.medpagetoday.com/Psychiatry/GeneralPsychiatry/dh/8509

ASM BIODEFENSE: Vaccine Protects Monkeys Against Ebola and Marburg Infection

WASHINGTON -- An experimental vaccine against both Ebola and Marburg virus protected 100% of vaccinated monkeys, whereas unvaccinated animals succumbed to infection, Army medical researchers reported here. full story

http://www.medpagetoday.com/PublicHealthPolicy/PublicHealth/dh/8508

Rule Shifts Would Let States Rework Medicaid Plans and Charge Patients More
WASHINGTON -- States would have greater latitude to craft their own Medicaid benefit packages and require increased cost sharing by patients, spell out two new regulations proposed by CMS. full story

http://www.medpagetoday.com/PublicHealthPolicy/Medicaid/dh/8507

Combination Strategy Works in Teens’ Refractory Depression

PITTSBURGH -- A change of antidepressants and the addition of cognitive behavioral therapy brought improvement for teens who did not respond to initial treatment for moderately severe, chronic depression. full story

http://www.medpagetoday.com/Psychiatry/Depression/dh/8503

Tissue-Sparing Radiation Dose Not Always as Prescribed

PHILADELPHIA -- In intensity-modulated radiation therapy (IMRT) there can be a substantial variation in the dose prescribed and that actually delivered to the tumor, depending on the software and equipment used, researchers here reported. full story

http://www.medpagetoday.com/Radiology/GeneralRadiology/dh/8506

Inexpensive Drug Found Best for Renoprotection from Contrast Agent

ANN ARBOR, Mich. -- For patients at a high risk of contrast-induced kidney failure, an inexpensive widely available pill is the most renoprotective agent of all, including hydration, found a meta-analysis here. full story

http://www.medpagetoday.com/Nephrology/GeneralNephrology/dh/8504

Annual Healthcare Spending Projected at $4.1 Trillion in 2017
WASHINGTON -- Spending in the U.S. on healthcare is expected to grow by 6.7% a year for a decade, reaching 19.6% of the gross domestic product by 2017, according to a report released today by the Centers for Medicare and Medicaid Services. full story

http://www.medpagetoday.com/PublicHealthPolicy/Medicare/dh/8501

Uterine Artery Embolization for Fibroids Found Good Alternative to Hysterectomy

AMSTERDAM -- Although uterine artery embolization and hysterectomy are both effective approaches to symptomatic fibroids, each has certain advantages, a study here found. full story

http://www.medpagetoday.com/OBGYN/Fibroids/dh/8500

Men and Women Differ in Responses to Intranasal Insulin

LUEBECK, Germany -- There is a gender gap in some responses to intranasal insulin, researchers here said. full story

http://www.medpagetoday.com/Endocrinology/Diabetes/dh/8499

Estrogen-Progestin Found to Blunt Sensitivity of Mammography

LOS ANGELES -- Use of estrogen plus progestin appears to make breast cancer more difficult to detect by both screening mammography and biopsy, according to a post hoc analysis of data from the Women’s Health Initiative study. full story

http://www.medpagetoday.com/HematologyOncology/BreastCancer/dh/8496

CME SPOTLIGHT

Managing CardioMetabolic Complexities
You are invited to participate in the following free educational activity where you will learn about the interrelated factors contributing to the metabolic syndrome and novel therapeutic strategies aimed at attenuating cardiometabolic risk while delaying disease progression.
Source: SciMed New York [more]

Lifelong Management of Parkinson's Disease: Diagnosis, Treatment and Emerging Therapies
A continuing education activity for physicians and pharmacists Update your knowledge on early and advanced stage Parkinson's disease (PD). Learn to assess neurobehavioral disorders in PD patients, review appropriate therapeutic options and plan optimal care of the PD patient.
Source: AAF-MED [more]

Heart Failure: From Emergency Department to Discharge
Join Drs. Frank Michota and Charles Emerman, as they provide the evidence-based science to support physicians in making critical decisions about appropriate ADHF management. This interactive CME activity will review effective diagnosis and treatment strategies in the ED, during admission, and after discharge to prevent rehospitalizations and improve patient healthcare outcomes.
Source: Med-IQ [more]

Waking Up to the Problem of OSA: Consequences and Improved Recognition
This neuroscienceCME VOICE activity will sharpen your awareness of OSA and arm you with screening tools and strategies to improve recognition and management, especially in populations that do not present with classic symptoms. Please register today.
Source: CME Outfitters [more]

New Frontiers in Targeted Therapy for Renal Cell Carcinoma
This activity is designed to educate clinicians on the most common malignancy of the kidney, renal cell carcinoma. Review evolving treatment strategies and best practices with Drs. Escudier, Eisen, and Rini.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Evolving Treatment Strategies for Hot Flashes: An Individualized Approach
This virtual symposium will compare and contrast treatment options available for vasomotor symptoms and the risks/benefits associated with each and evaluate the latest data available to formulate patient-specific treatment plans.
Source: The Chatham Institute [more]

The Science and Strategy of Biopreparedness: Critical Agent Update and Emerging Disease Threats
This activity employs an expert faculty to explore state-of-the-art knowledge about potential biological threats (Avian Influenza, Smallpox and Toxins), preventive measures and treatments currently available and on the horizon.
Source: Annenberg Center for Health Sciences at Eisenhower [more]

Advancing Patient Care in IBD: A Clinically Relevant Perspective
The following CME certified webcast brings participants clinical pearls from national and international experts in the area of IBD. The clinical utility of conventional agents and available biologic therapies are reviewed. Chaired by Dr. Gary Lichtenstein.
Source: University of Pennsylvania School of Medicine [more]

Impact of ADHD and Its Treatment on Substance Abuse
Join Dr. Timothy Wilens in an in-depth CME activity as he discusses emerging data on the impact of ADHD and its treatment on substance use disorder, especially as related to adolescents and adults.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Management of Recurrent Metastatic NSCLC - Chronic Treatment with Biologic Agents
Illustrated by a relevant case study, Roy S. Herbst, MD, PhD, examines the current thinking on selecting patients with advanced NSCLC for EGFR genetic testing and treatment with EGFR inhibitors. Includes expert audio commentary by Corey J. Langer, MD, FACP.
Source: Projects In Knowledge [more]

Genital HPV and HPV Vaccines: Winning acceptance among adolescents and their parents
HPV is a highly prevalent sexually transmitted infection, most common in sexually active women under the age of 25. The following free educational activity is designed to educate physicians about the most common types of genital HPV and review the safety and efficacy of utilizing HPV vaccines.
Source: SciMed New York [more]

Managing the Symptomatic Menopausal Patient in Primary Care: A Case-Based Approach
This interactive CME activity provides practical recommendations and the latest clinical evidence to improve the personalized care a women receives during menopause.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Excessive Sleepiness: A Neglected Area of Risk?
Learn to recognize excessive sleepiness and manage its consequences in this neuroscienceCME webcast. Filmed at worldsleep07 in Cairns, Australia, this presentation features the world's leading sleep specialists and offers multidisciplinary credit.
Source: CME Outfitters [more]

RESOURCES

Now Approved: A new development in the treatment of hypertension.
Now approved from Forest Laboratories: Bystolic (nebivolol). A novel beta blocker for the treatment of hypertension. Click here to learn more. Source: Forest Labs [more]

Explore the Possibilities in Type 2 Diabetes.
Explore the Possibilities in Type 2 Diabetes. Source: Merck [more]

Take a closer look at all 3 major lipids and cardiovascular risk. HDL, LDL and TG levels may be independently associated with cardiovascular risk.
Visit www.totallipds.com, a new source of information for health care professionals, about dyslipidemia, all 3 lipids, and cardiovascular risk. Source: Merck [more]

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ASCO GI Meeting

ASCO GI: Sunitinib Shows Good Real-World Imatinib-Resistant GIST Results

CHF

Statins Cut Death Rates in Heart Failure

Arthritis

Rituximab Meets Primary Endpoint as First-Line RA Biologic Therapy

General Nephrology

Surgical ICU Patients Benefit Most from Intensive Insulin

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