Daily Headlines

PUTTING BREAKING MEDICAL NEWS INTO PRACTICE^™

Thursday February 28, 2008

TODAY'S HEADLINES
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Did you know that you can earn CME/CE credit by reading our news reports? Look for the CME designation after the article title.

Vasopressin Offers No Survival Benefit for Septic Shock

VANCOUVER, British Columbia -- Low-dose vasopressin does not reduce septic shock mortality when used as an adjunct to conventional catecholamine vasopressors, according to a randomized controlled trial. full story

http://www.medpagetoday.com/PublicHealthPolicy/PublicHealth/dh/8505

Survey What Should the FDA Do About Reprint Marketing?

The FDA has issued draft guidelines that would permit marketing of FDA-approved drugs via scientific reprints that discuss unapproved indications -- currently a forbidden practice. Vote

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CT and MRI Score in Detecting Wrist Bone Erosion in RA

HVIDOVRE, Denmark -- Both CT and MRI are more sensitive than radiography, the standard imaging technique, for detecting early erosion of the wrist bone in rheumatoid arthritis, researchers found. full story

http://www.medpagetoday.com/Rheumatology/Arthritis/dh/8525

Weight-Loss Trial Update: Journalist Discovers Will Power

NEW ORLEANS -- I’m a few days short of a month into my participation in a randomized, placebo- controlled trial of an investigational weight-loss drug -- and I can report that I’m a fast starter. full story

http://www.medpagetoday.com/Cardiology/Prevention/dh/8513

Anti-HIV Gel Found Safe for Daily Use as Putative Microbicide

NEW DELHI -- Women may safely use a vaginal gel containing an anti-HIV drug on a daily basis, researchers here said, but the microbicide’s efficacy against the virus has not been tested. full story

http://www.medpagetoday.com/HIVAIDS/HIVAIDS/dh/8518

Herbal Supplement May Protect Memory After Age 85

CORVALLIS, Ore. -- The popular plant supplement ginkgo biloba may help preserve memory in older octogenarians, but it may increase the risk of stroke, researchers found. full story

http://www.medpagetoday.com/PrimaryCare/AlternativeMedicine/dh/8523

Hepatoxicity Warning Added to Natalizumab (Tysabri) Label
ROCKVILLE, Md. -- The multiple sclerosis drug natalizumab (Tysabri) may cause clinically significant liver injury, which can occur as early as six days after the initial dose, according to the FDA. full story

http://www.medpagetoday.com/ProductAlert/Prescriptions/dh/8522

Analysis Gives Venlafaxine Slender Edge Over SSRIs

ATLANTA -- For achieving major depression remission, a dual neurotransmitter reuptake inhibitor has a thin advantage over selective serotonin reuptake inhibitors, found a meta-analysis. full story

http://www.medpagetoday.com/Psychiatry/Depression/dh/8520

WHO Finds Global Drug-Resistant TB at Record Levels
GENEVA -- Cases of multidrug-resistant tuberculosis have reached record levels worldwide and extensively drug-resistant tuberculosis (XDR-TB) has spread to 45 countries, according to the World Health Organization. full story

http://www.medpagetoday.com/Pulmonary/Tuberculosis/dh/8521

Potential Blood Test for Mood Disorders Seen in Biomarker Panel

INDIANAPOLIS -- A blood test for mood disorders that enables better diagnosis and treatment may be feasible, researchers here said. full story

http://www.medpagetoday.com/Genetics/GeneticTesting/dh/8519

Skipping Insulin Doses to Manage Weight Risks Death

BOSTON -- Women with type 1 diabetes who take less insulin than they should as a form of calorie purging are at a three-fold higher mortality risk, researchers found. full story

http://www.medpagetoday.com/Endocrinology/Diabetes/dh/8517

Toremifene (Acapodene) Reduces Fracture Risk from Androgen Deprivation Therapy

MEMPHIS, Tenn. -- In men treated with androgen deprivation for prostate cancer, an anti-estrogen agent has reduced the rate of osteoporotic fractures by half, according to phase III trial data issued by the drug maker in a press release. full story

http://www.medpagetoday.com/Urology/ProstateCancer/dh/8514

Childhood Obesity Sets Latinos Up for Lifetime of Complications

BOSTON -- Obesity in otherwise healthy Latino children may kick-start inflammatory processes that lead to cardiovascular disease and type 2 diabetes, researchers here found. full story

http://www.medpagetoday.com/Pediatrics/Obesity/dh/8492

CME SPOTLIGHT

Managing CardioMetabolic Complexities
You are invited to participate in the following free educational activity where you will learn about the interrelated factors contributing to the metabolic syndrome and novel therapeutic strategies aimed at attenuating cardiometabolic risk while delaying disease progression.
Source: SciMed New York [more]

Lifelong Management of Parkinson's Disease: Diagnosis, Treatment and Emerging Therapies
A continuing education activity for physicians and pharmacists Update your knowledge on early and advanced stage Parkinson's disease (PD). Learn to assess neurobehavioral disorders in PD patients, review appropriate therapeutic options and plan optimal care of the PD patient.
Source: AAF-MED [more]

Hepatitis C: From Scientific Foundations to New Vistas in Treatment
This webcast explores what is known about the HCV life cycle, host immune response to HCV, and nonresponse to treatment, and provides updates on the latest STAT-C agents and other novel HCV treatments.
Source: Projects In Knowledge [more]

Targeted Cancer Therapy From Trial To Clinic
Join Drs. Balducci, Atkins, Cantley, and Herbst for an innovative and in-depth CME-certified Activity on how integration of targeted and conventional therapies for treating cancer is improving patient outcomes.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Waking Up to the Problem of OSA: Consequences and Improved Recognition
This neuroscienceCME VOICE activity will sharpen your awareness of OSA and arm you with screening tools and strategies to improve recognition and management, especially in populations that do not present with classic symptoms. Please register today.
Source: CME Outfitters [more]

Adequate Relief: Optimal Opioid Dosing and Side-Effect Management for Long-Term Care Patients
This CME/CE certified monograph addresses optimal opioid dosing and side effect management for long-term care patients.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Preserving the Integrity of Future Treatment: ARV Regimens, Subsequent Choices, and the Cost of Resistance
Register today for a live CME/CE Consult with the HIV Experts Webinar to learn more about initial antiretroviral regimens, downstream options, early failure, and potential resistance implications.
Source: AdvancMed [more]

neuroscienceCME Journal Club
Trouble keeping up with the latest findings from the clinical literature? neuroscienceCME Journal Club can help. Hear leading authors talk about just-published articles, and then answer your questions. Hosted by Thomas Roth, PhD.
Source: CME Outfitters [more]

Evolving Treatment Strategies for Hot Flashes: An Individualized Approach
This virtual symposium will compare and contrast treatment options available for vasomotor symptoms and the risks/benefits associated with each and evaluate the latest data available to formulate patient-specific treatment plans.
Source: The Chatham Institute [more]

Managing the Symptomatic Menopausal Patient in Primary Care: A Case-Based Approach
This interactive CME activity provides practical recommendations and the latest clinical evidence to improve the personalized care a women receives during menopause.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Novel Insights Into Cardiometabolic Disease
Hypertension is a major risk factor for the development of both cardiovascular and renal disease in patients with diabetes. The following certified webcast offers cardiometabolic disease management strategies that can be applied across diverse patient populations.
Source: SciMed New York [more]

Emerging Trends in the Treatment of Renal Cell Carcinoma
Drs. Michael B. Atkins, Bernard J. Escudier, and Gary R. Hudes lead this CME activity which examines current and evolving standards of care for the treatment of early stage and advanced renal cell carcinoma; best practices for optimal patient outcomes are also covered.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Insight Into Depression Interactive Case Study: Symptoms of Depression in a Middle-aged Patient with Type 2 Diabetes: Confirming the Diagnosis
Designed for primary care physicians, this activity will improve the care of patients affected by major depressive disorders. Incorporates the principles of current practice guidelines and best available clinical management resources into individual practices.
Source: The University of Pennsylvania School of Medicine [more]

JOURNAL DOWNLOADS

Efficacy Data for CTCL Published in JCO
Efficacy Data for CTCL Published in JCO. Source: Merck. [more]

RESOURCES

Now Approved: A new development in the treatment of hypertension.
Now approved from Forest Laboratories: Bystolic (nebivolol). A novel beta blocker for the treatment of hypertension. Click here to learn more. Source: Forest Labs [more]

Take a closer look at all 3 major lipids and cardiovascular risk. HDL, LDL and TG levels may be independently associated with cardiovascular risk.
Visit www.totallipds.com, a new source of information for health care professionals, about dyslipidemia, all 3 lipids, and cardiovascular risk. Source: Merck [more]

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ASCO GI Meeting

ASCO GI: Sunitinib Shows Good Real-World Imatinib-Resistant GIST Results

CHF

Statins Cut Death Rates in Heart Failure

Arthritis

Rituximab Meets Primary Endpoint as First-Line RA Biologic Therapy

General Nephrology

Surgical ICU Patients Benefit Most from Intensive Insulin

Get tools, resources & information about Gleevec matching the experience of attendees of the 2007 ASH Annual Meeting.

Did you miss the Gleevec booth at the 2007 ASH Meeting? Get tools, resources and information about Gleevec via a fully interactive virtual exhibit booth, matching the experience of attendees of the 2007 ASH Annual Meeting.

Source: Novartis Oncology.

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