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PUTTING BREAKING MEDICAL NEWS INTO PRACTICE^™

Monday February 25, 2008

TODAY'S HEADLINES
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For the latest news, features, columns, video and audio reports and more, visit our home page at www.medpagetoday.com

ASA: Late Thrombolytic Therapy Does Not Reduce Infarct Size

NEW ORLEANS -- Thrombolytic therapy given three to six hours after symptom onset -- beyond the approved therapeutic window -- did not limit infarct growth in patients who theoretically might benefit from late reperfusion, investigators reported here. full story

http://www.medpagetoday.com/MeetingCoverage/ASAMeeting/dh/8479

Survey What Should the FDA Do About Reprint Marketing?

The FDA has issued draft guidelines that would permit marketing of FDA-approved drugs via scientific reprints that discuss unapproved indications -- currently a forbidden practice. Vote

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Awareness of Heart Attack Symptoms Is Low

ATLANTA -- Although awareness of individual warning signs of heart attack and stroke is high, few Americans know all the symptoms or what to do about them, CDC researchers said. full story

http://www.medpagetoday.com/Cardiology/MyocardialInfarction/dh/8474

Extreme Makeover Planned for Flu Vaccine

ATLANTA -- Next season’s influenza vaccine recipe is set for a complete overhaul, but a CDC official downplayed speculation that delays or shortages could result. full story

http://www.medpagetoday.com/InfectiousDisease/URItheFlu/dh/8473

FDA Okays Bevacizumab (Avastin) for Metastatic Breast Cancer
ROCKVILLE, Md. -- The FDA today approved bevacizumab (Avastin) in combination with paclitaxel (Taxol) for chemotherapy-na�ve patients with metastatic HER2-negative breast cancer. full story

http://www.medpagetoday.com/ProductAlert/Prescriptions/dh/8476

Vitamin E Supplements Plus High Dietary Vitamin C May Lead to TB in Smokers

HELSINKI, Finland -- The investigators who first punctured the vitamin E balloon are still at it. This time they found that vitamin E supplements along with diets rich in vitamin C may predispose men who smoke heavily to tuberculosis. full story

http://www.medpagetoday.com/PrimaryCare/PreventiveCare/dh/8475

Updated Osteoporosis Guideline Addresses a Broader Population

WASHINGTON -- Non-Caucasian women and men over 50 are covered for the first time in new guidelines for prevention and treatment of osteoporosis issued here by the National Osteoporosis Foundation. full story

http://www.medpagetoday.com/Endocrinology/Osteoporosis/dh/8471

Obesity Associated with Pediatric Surgery Complications

ANN ARBOR, Mich. -- Obese children and adolescents seem to have an elevated risk of perioperative respiratory complications from common elective operations, researchers here found. full story

http://www.medpagetoday.com/Surgery/Anesthesiology/dh/8442

ASA: A Little Fitness Goes a Long Way in Primary Stroke Prevention

NEW ORLEANS -- Hitting the road or track for a half hour regularly can reduce stroke risk by at least 40%, according to a longitudinal study of more than 60,000 adults. full story

http://www.medpagetoday.com/MeetingCoverage/ASAMeeting/dh/8470

Swimming Pool Exercises May Offer Cost-Effective Help in Fibromyalgia

CACERES, Spain -- Supervised exercises in a waist-deep pool of warm water may offer a cost-effective adjunctive therapy for fibromyalgia, investigators here reported. full story

http://www.medpagetoday.com/Rheumatology/Fibromyalgia/dh/8469

Vitamins Found No Help for Down’s Syndrome Children

EXETER, England -- Children with Down’s syndrome did not improve their development with the use of antioxidant vitamins, researchers found. full story

http://www.medpagetoday.com/Pediatrics/GeneralPediatrics/dh/8468

ASA: Nodding Off During the Day Indicates Higher Risk of Stroke

NEW ORLEANS -- People in their 70s who doze frequently during daytime activities are at an increased risk for stroke and other vascular events, showed a community-based cohort study. full story

http://www.medpagetoday.com/MeetingCoverage/ASAMeeting/dh/8452

CME SPOTLIGHT

Overview of Menopause: The Cycle of Vasomotor Disturbances
This virtual symposium will help clinicians who treat patients with vasomotor symptoms evaluate the latest data available to formulate patient-specific treatment plans, and will familiarize physicians with the need to communicate with their patients on alternative therapies and how those therapies may interact with prescription medications.
Source: The Chatham Institute [more]

Waking Up to the Problem of OSA: Consequences and Improved Recognition
This neuroscienceCME VOICE activity will sharpen your awareness of OSA and arm you with screening tools and strategies to improve recognition and management, especially in populations that do not present with classic symptoms. Please register today.
Source: CME Outfitters [more]

New Frontiers in Targeted Therapy for Renal Cell Carcinoma
This activity is designed to educate clinicians on the most common malignancy of the kidney, renal cell carcinoma. Review evolving treatment strategies and best practices with Drs. Escudier, Eisen, and Rini.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Adequate Relief: Optimal Opioid Dosing and Side-Effect Management for Long-Term Care Patients
This CME/CE certified monograph addresses optimal opioid dosing and side effect management for long-term care patients.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Management of Recurrent Metastatic NSCLC?Chronic Treatment with Biologic Agents
Illustrated by a relevant case study, Roy S. Herbst, MD, PhD, examines the current thinking on selecting patients with advanced NSCLC for EGFR genetic testing and treatment with EGFR inhibitors. Includes expert audio commentary by Corey J. Langer, MD, FACP.
Source: Projects In Knowledge [more]

Genital HPV and HPV Vaccines: Winning acceptance among adolescents and their parents
HPV is a highly prevalent sexually transmitted infection, most common in sexually active women under the age of 25. The following free educational activity is designed to educate physicians about the most common types of genital HPV and review the safety and efficacy of utilizing HPV vaccines.
Source: SciMed New York [more]

Who Moved My PEG? The Changing Future of Anti-HCV Therapy
This CME webcast provides information on HCV epidemiology and disease burden, goals for treatment success, methods for minimizing treatment resistance and current and emerging approaches to anti-HCV therapy.
Source: Projects In Knowledge [more]

Depressive Symptoms in an Elderly Patient: Sorting Out the Alternatives
The following certified educational series is designed to help primary care clinicians recognize the signs and symptoms of major depressive disorders. The participant will review evidence-based management strategies for elderly patients with major depressive disorders and medical co- morbidities.
Source: The University of Pennsylvania School of Medicine [more]

New phase 3 trials may dramatically alter the management of newly diagnosed myeloma.
This activity reviews these trials as well as new developments in transplantation and relapsed/refractory therapies.
Source: Curatio CME Institute [more]

Emerging Patient Challenges in COPD: Interactive Case Simulator
Designed for primary care clinicians. This case-based CME activity provides a virtual learning experience, allowing participants to order diagnostic tests, prescribe drugs, diagnose and develop new treatment strategies; simulating clinical practice.
Source: CASIVUS [more]

Pathophysiology of Vasomotor Symptoms: Thermoregulatory and Cognitive Issues
This virtual symposium will help clinicians to better recognize factors contributing to the pathophysiology of vasomotor symptoms, and evaluate the latest data available to formulate patient-specific treatment plans.
Source: The Chatham Institute [more]

Emerging Trends in the Treatment of Renal Cell Carcinoma
Drs. Michael B. Atkins, Bernard J. Escudier, and Gary R. Hudes lead this CME activity which examines current and evolving standards of care for the treatment of early stage and advanced renal cell carcinoma; best practices for optimal patient outcomes are also covered.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Novel Insights Into Cardiometabolic Disease
Hypertension is a major risk factor for the development of both cardiovascular and renal disease in patients with diabetes. The following certified webcast offers cardiometabolic disease management strategies that can be applied across diverse patient populations.
Source: SciMed New York [more]

JOURNAL DOWNLOADS

Efficacy Data for CTCL Published in JCO
Efficacy Data for CTCL Published in JCO. Source: Merck. [more]

RESOURCES

Now Approved: A new development in the treatment of hypertension.
Now approved from Forest Laboratories: Bystolic (nebivolol). A novel beta blocker for the treatment of hypertension. Click here to learn more. Source: Forest Labs [more]

Explore the Possibilities in Type 2 Diabetes.
Explore the Possibilities in Type 2 Diabetes. Source: Merck [more]

Take a closer look at all 3 major lipids and cardiovascular risk. HDL, LDL and TG levels may be independently associated with cardiovascular risk.
Visit www.totallipds.com, a new source of information for health care professionals, about dyslipidemia, all 3 lipids, and cardiovascular risk. Source: Merck [more]

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APSS Meeting

APSS: Extra Health Cost of Insomnia Reaches $3,200 an Employee

AGS Meeting

AGS: Methylnaltrexone Demonstrates Efficacy for Treatment of Opioid-Induced Constipation

ACC Meeting

ACC: Mixed Messages on Heart Failure Disease Management

ASCO Meeting

ASCO: Chemotherapy Doesn't Help in Malignant Mesolthelioma

Get tools, resources & information about Gleevec matching the experience of attendees of the 2007 ASH Annual Meeting.

Did you miss the Gleevec booth at the 2007 ASH Meeting? Get tools, resources and information about Gleevec via a fully interactive virtual exhibit booth, matching the experience of attendees of the 2007 ASH Annual Meeting.

Source: Novartis Oncology.

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