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Brain Monitoring Fails to Prevent Anesthesia Awareness

ST. LOUIS -- Surgical patients managed with a popular brain function monitor are no less likely to be aware of what’s going on during the procedure as those managed with a more traditional method, researchers here said. full story

http://www.medpagetoday.com/Surgery/Anesthesiology/dh/8686

Survey The FDA and Heparin

Despite a report of 389 adverse events, including four deaths, the FDA did not demand immediate withdrawal of Baxter’s heparin products, saying that would have caused a severe shortage of the drug. More than two weeks later, the company voluntarily withdrew all multi-dose and single-dose vials. Vote

OTHER MEDPAGE TODAY EXTRAS

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FDA Extends Anemia Drug Warning to Cervical Cancer
ROCKVILLE, Md.-- Cervical cancer has been added to the list of malignancies that are worsened by aggressive use of the erythropoiesis-stimulating agents darbepoetin alfa (Aranesp) and epoetin alfa (Epogen, Procrit), according to the FDA. full story

http://www.medpagetoday.com/ProductAlert/Prescriptions/dh/8713

Gene Methylation Patterns Predict Early-Stage NSCLC Recurrence

BALTIMORE -- The risk of recurrence of stage I non-small-cell lung cancer can be predicted by a group of four genes, researchers here said. full story

http://www.medpagetoday.com/Pulmonary/LungCancer/dh/8700

Cetuximab (Erbitux)-Induced Anaphylaxis May Be Avoidable

CHARLOTTESVILLE, Va. -- The unusual but severe allergic reactions to the cancer agent cetuximab (Erbitux), a monoclonal antibody, appear to be caused by preexisting immunoglobulin E (IgE) antibodies, researchers here found. full story

http://www.medpagetoday.com/HematologyOncology/ColonCancer/dh/8689

New Kidney Injury Marker Validated in Children

CINCINNATI -- Evidence is mounting that urinary levels of neutrophil gelatinase-associated lipocalin are a more clinically useful marker of acute kidney injury after cardiopulmonary bypass surgery than serum creatinine, researchers here said. full story

http://www.medpagetoday.com/Nephrology/GeneralNephrology/dh/8711

CDC Cites Continuing Syphilis Resurgence

CHICAGO -- New cases of syphilis in the U.S. rose 12% in one year, from 2006 to 2007, CDC officials said here today. full story

http://www.medpagetoday.com/InfectiousDisease/STDs/dh/8710

SGO: Extended Chemotherapy May Reduce Recurrence in Ovarian Cancer

TAMPA, Fla. -- In high-risk, early-stage ovarian cancer, six cycles of adjuvant chemotherapy significantly improves recurrence-free survival, but only for patients with serous tumors, an exploratory analysis of data from a multicenter trial showed. full story

http://www.medpagetoday.com/MeetingCoverage/SGO/dh/8697

Blacks Hit Harder by Idiopathic Intracranial Hypertension

ATLANTA -- In pseudotumor cerebri, a rare condition also called idiopathic intracranial hypertension, blacks are more likely to become legally blind than whites, Hispanics, and Asians, a single-center study showed. full story

http://www.medpagetoday.com/Neurology/GeneralNeurology/dh/8707

Maternal Obesity Only Weakly Linked to Child’s Obesity

BRISTOL, England -- A woman’s high pre- pregnancy body mass index (BMI) and a genetic indicator of maternal fatness do not destine her child to become fat, researchers here reported. full story

http://www.medpagetoday.com/Pediatrics/Obesity/dh/8706

SGO: Postop Glucose Spike Predicts Complications in Ovarian Cancer

TAMPA, Fla. -- A spike in blood glucose after cytoreductive surgery for ovarian cancer may signal impending complications, findings from a retrospective chart review suggest. full story

http://www.medpagetoday.com/MeetingCoverage/SGO/dh/8705

Chemotherapy Offers Little Benefit for Localized Stomach Cancer

FLORENCE, Italy -- Combination chemotherapy may not improve survival for nonmetastatic gastric cancer after surgery, results of a randomized clinical trial suggested. full story

http://www.medpagetoday.com/HematologyOncology/OtherCancers/dh/8704

CME SPOTLIGHT

Evolution in the Use of Boosted PIs as First-line Therapy: Factors to Consider
Drs Graeme Moyle and Sharon Walmsley review studies that compare efficacy, safety, and metabolic parameters of PIs in head-to-head trials along with emerging data on drug-drug interactions and insulin resistance.
Source: AdvancMed [more]

Targeted Cancer Therapy From Trial To Clinic
Join Drs. Balducci, Atkins, Cantley, and Herbst for an innovative and in-depth CME-certified Activity on how integration of targeted and conventional therapies for treating cancer is improving patient outcomes.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Controversies and Consensus in the Management of HIV: Interactive Debates
Are NNRTI- or PI-based regimens the best choice for initial ARV therapy? If a patient is failing therapy, when should you switch? Do treatment experienced patients require 2 or 3 active ARV agents? Join us for thoughtful debates and lively discussion led by a panel of HIV experts.
Source: AdvancMed [more]

New Frontiers in Targeted Therapy for Renal Cell Carcinoma
This activity is designed to educate clinicians on the most common malignancy of the kidney, renal cell carcinoma. Review evolving treatment strategies and best practices with Drs. Escudier, Eisen, and Rini.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Managing the Symptomatic Menopausal Patient in Primary Care: A Case-Based Approach
This interactive CME activity provides practical recommendations and the latest clinical evidence to improve the personalized care a women receives during menopause.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Novel Insights Into Cardiometabolic Disease
Hypertension is a major risk factor for the development of both cardiovascular and renal disease in patients with diabetes. The following certified webcast offers cardiometabolic disease management strategies that can be applied across diverse patient populations.
Source: SciMed New York [more]

neuroscienceCME Journal Club
Trouble keeping up with the latest findings from the clinical literature? neuroscienceCME Journal Club can help. Hear leading authors talk about just-published articles, and then answer your questions. Hosted by Thomas Roth, PhD.
Source: CME Outfitters [more]

Insight Into Depression Interactive Case Study: Symptoms of Depression in a Middle-aged Patient with Type 2 Diabetes: Confirming the Diagnosis
Designed for primary care physicians, this activity will improve the care of patients affected by major depressive disorders. Incorporates the principles of current practice guidelines and best available clinical management resources into individual practices.
Source: The University of Pennsylvania School of Medicine [more]

JOURNAL DOWNLOADS

First-line SUTENT® data recently published in NEJM
Read first-line SUTENT data in the New England Journal of Medicine. Get it at SUTENThcp.com Source: Pfizer [more]

Efficacy Data for CTCL Published in JCO
Efficacy Data for CTCL Published in JCO. Source: Merck. [more]

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