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Medical Studies/Trials News Shorter radiotherapy courses for breast cancer just as safe and effective
http://www.news-medical.net/?id=36527
British researchers say when it comes to treating breast cancer in women, shorter courses of radiation at a lower overall dose appear to be just as safe and effective as the standard treatment delivered over a longer period of time.

Hispanics with clogged arteries at greatest risk of stroke, heart attack
http://www.news-medical.net/?id=36500
Hispanics who have even a small amount of plaque build-up in the neck artery that supplies blood to the brain are up to four times more likely to suffer or die from a stroke or heart attack than Hispanics who do not have plaque, according to a study published in the March 19, 2008, online issue of Neurology, the medical journal of the American Academy of Neurology.

Price of medicine may affect its efficacy
http://www.news-medical.net/?id=36510
You are offered two painkillers, one selling at full price for $2.50 per pill and the other discounted to 10 cents each.

Winners don't punish
http://www.news-medical.net/?id=36512
Individuals who engage in costly punishment do not benefit from their behavior, according to a new study published this week in the journal Nature by researchers at Harvard University and the Stockholm School of Economics.

New study confirms that PROGENSA PCA3 can improve accuracy of prostate cancer diagnosis
http://www.news-medical.net/?id=36506
New clinical data from a study of 570 men published in the peer-reviewed Journal of Urology support the use of PROGENSA PCA3 as a tool for diagnosing prostate cancer. The study confirms that PROGENSA PCA3, the world's first gene-based urine test to help detect prostate cancer, can provide clinicians with valuable information that helps guide diagnosis.

Battle against obesity could be tackled one community at a time
http://www.news-medical.net/?id=36487
The battle against obesity in this country could be tackled one community at a time, according to a newly published study in the Journal of Physical Activity and Health. Researchers at the University of Colorado at Denver demonstrated the effectiveness of changing behaviors at a community level, suggesting that community-based interventions could be a viable option to address the nation's obesity epidemic.

Cortisol provide relief for chronic fatigue syndrome and fibromyalgia sufferers
http://www.news-medical.net/?id=36489
Chronic fatigue syndrome (CFS) and fibromyalgia (FM) are two serious and debilitating diseases with no confirmed cause and limited treatment options.

Caregivers with depressive symptoms not warm to children
http://www.news-medical.net/?id=36491
A new study in the journal Family Process reveals that caregivers with moderate to severe depressive symptoms showed greater hostility and less warmth.

Shorter radiotherapy courses can benefit breast cancer patients
http://www.news-medical.net/?id=36518
A LOWER total dose of radiotherapy, delivered in fewer, larger treatments has been shown to be as effective as the international standard of a higher total dose delivered over a longer time to treat women with early breast cancer according to new research published in the Lancetand Lancet Oncology.

Review of supplement use among US cancer patients
http://www.news-medical.net/?id=36525
Many of the 10 million cancer patients in the US are taking nutritional supplements, but an accurate assessment of the frequency is not well appreciated.

Cholesterol-associated gene variants can predict cardiovascular events
http://www.news-medical.net/?id=36522
A study appearing in this week's New England Journal of Medicine confirms that a combination of gene variants previously associated with cholesterol levels does reflect patients' cholesterol levels and can signify increased risk of heart attack, stroke or sudden cardiac death.

Vegan diet for rheumatoid arthritis patients protects from heart attacks and strokes
http://www.news-medical.net/?id=36473
A new study suggests that following a gluten-free, vegan diet may offer rheumatoid arthritis patients some protection from heart attacks and strokes.

New interventional radiology treatment shows promise for complications from bone marrow, stem cell tranplants
http://www.news-medical.net/?id=36445
The standard treatment to treat graft-versus-host disease (GVHD) after bone marrow or cord blood transplant is intravenous (IV) steroids that alter the immune response; however, it is not always effective and failure results in very high mortality.

How is H pylori adhesion to gastric cells associated with MUC1 mucin VNTR size?
http://www.news-medical.net/?id=36436
The Gram negative bacterium H pylori is involved in the pathogenesis of several gastrointestinal diseases, ultimately leading to gastric carcinoma.

What change does prokineticin 2/Bv8 have in human hepatocellular carcinoma?
http://www.news-medical.net/?id=36465
Liver hepatocarcinoma is a highly vascularized cancer, and more and more research is focused on the molecules controlling angiogenesis.

Lithium chloride slows development of inclusion body myositis
http://www.news-medical.net/?id=36440
A new UC Irvine study finds that lithium chloride, a drug used to treat bipolar disorder, can slow the development of inclusion body myositis, a skeletal muscle disease that affects the elderly.

Increased hepcidin expression: A novel oncogenic signalling mechanism
http://www.news-medical.net/?id=36437
Historically anaemia, which is associated with colorectal cancer, has been attributed to blood loss.

Variants of the gene LRP5 associated with increased risk of bone fractures, low bone mineral density
http://www.news-medical.net/?id=36430
Results from a large study indicate that variants of the gene LRP5 are associated with a significant increase in the risk of fractures, by up to 20 percent, and lower levels of bone mineral density in the spine and hip, according to a study in the March 19 issue of JAMA, a theme issue on Genetics and Genomics.

Treating chronic post-traumatic stress disorder with psychotherapy
http://www.news-medical.net/?id=36418
A randomized controlled trial by Lyon investigators discloses the difficulties in treating chronic posttraumatic stress disorder with psychotherapy in the March issue of Psychotherapy and Psychosomatics.

MedImmune advances clinical development of antibody targeting interleukin-9 in patients with asthma
http://www.news-medical.net/?id=36443
MedImmune has announced that its clinical program studying an investigational treatment targeting interleukin-9 (IL-9) has advanced with the start of a new trial in patients with asthma.

Psychological stress resulting from the traumatic stress may damage this brain
http://www.news-medical.net/?id=36422
Individuals who experience military combat obviously endure extreme stress, and this exposure leaves many diagnosed with the psychiatric condition of post-traumatic stress disorder, or PTSD.

Only two per cent of 700 paediatric drug trials included independent safety checks
http://www.news-medical.net/?id=36439
Only two per cent of paediatric drug trials reported that they had established independent safety monitoring committees that can help lead to the early detection of adverse drug reactions, according to a major review in the April issue of Acta Paediatrica.

HDL-associated protein gene linked to heart disease risk
http://www.news-medical.net/?id=36434
The gene for the HDL-associated protein paraoxonase 1 (PON1) appears to be associated with coronary artery disease and with the risk of developing adverse cardiac events, and variations in both the PON1 gene and its related enzyme activity may increase the risk for cardiovascular disease events, according to a study in the March 19 issue of JAMA , a theme issue on Genetics and Genomics.

Uric acid in the blood may be an early sign of diabetic kidney disease
http://www.news-medical.net/?id=36463
For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

The effect of melatonin on colitis
http://www.news-medical.net/?id=36466
In rats with experimental colitis, the marked increase in bacterial translocation in postcolitis rats has been reversed by melatonin administration.

Do bacterial combinations result in enhanced cytokine production? No!
http://www.news-medical.net/?id=36421
Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have been used for the prevention and treatment of a diverse range of disorders.

New choices bring wider range of women to family planning
http://www.news-medical.net/?id=36444
A study appearing in the March 2008 issue of the journal Contraception reports that the Standard Days Method, a natural family planning method developed by researchers from Georgetown University Medical Center's Institute for Reproductive Health, brings new women to family planning.

Past child abuse plus variations in gene result in potent PTSD risk for adults
http://www.news-medical.net/?id=36448
A traumatic event is much more likely to result in posttraumatic stress disorder (PTSD) in adults who experienced trauma in childhood - but certain gene variations raise the risk considerably if the childhood trauma involved physical or sexual abuse, scientists have found.

Body mass index higher among bariatric surgery patients with 2 genetic variations
http://www.news-medical.net/?id=36365
The combination of two obesity-related genetic variations may be associated with an increased body mass index (BMI) among severely obese patients undergoing bariatric weight loss surgery, according to a report in the March issue of Archives of Surgery.

An anti-inflammatory response to the vegan diet
http://www.news-medical.net/?id=36362
Rheumatoid arthritis (RA) patients who eat a gluten-free vegan diet could be better protected against heart attacks and stroke.

Trial of injectable microfoam for varicose veins
http://www.news-medical.net/?id=36379
A small group of patients with a common heart defect who were treated for varicose veins with an injectable microfoam experienced no neurological, visual or cardiac changes as a result of the treatment, according to preliminary results from a phase II trial.

White matter and balance in old age
http://www.news-medical.net/?id=36394
New research shows how well people get around and keep their balance in old age is linked to the severity of changes happening in their brains.

NanoBio successfully completes phase 2b study in Herpes labialis
http://www.news-medical.net/?id=36384
NanoBio Corporation reported top-level findings from its phase 2b study of NB-001, a topical lotion to treat herpes labialis (cold sores).

Neighborhoods play role in how much people exercise
http://www.news-medical.net/?id=36385
The neighborhoods people live in can help inspire - or discourage - their residents to exercise and keep physically active, new research suggests.

Pycnogenol improves memory of senior citizens
http://www.news-medical.net/?id=36389
New research accepted for publication in the Journal of Psychopharmacology, demonstrates Pycnogenol, (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, improves the memory of senior citizens.

Keeping middle schoolers from alcohol is a tougher task in the inner city than in rural areas
http://www.news-medical.net/?id=36375
A three-year, three-pronged prevention program did little to keep Chicago middle schoolers from drinking or using drugs, despite its prior success in rural Minnesota, where the program reduced alcohol use 20 to 30 percent, UF and University of Minnesota researchers recently reported in the online edition of the journal Addiction.

Long-term follow-up after percutaneous pulmonary radiofrequency ablation
http://www.news-medical.net/?id=36406
Radiofrequency ablation (RFA) - an interventional treatment that "cooks" and kills lung cancer tumors with heat - greatly improves survival time from primary or metastatic inoperable lung tumors, according to a study released at the Society of Interventional Radiology's 33rd Annual Scientific Meeting.

Uric acid may provide early clues to diabetic kidney disease
http://www.news-medical.net/?id=36407
For patients with type 1 diabetes, increased levels of uric acid in the blood may be an early sign of diabetic kidney disease - appearing before any significant change in urine albumin level, the standard screening test, reports a study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology.

Sex, age, burn site associated with abnormal scarring after burn injury
http://www.news-medical.net/?id=36409
Sex, age, burn site, number of surgical procedures and the type of skin graft are associated with abnormal scarring following burns, according to a report in the March/April 2008 issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.

Study examines changes in quality of life after head and neck cancer treatment
http://www.news-medical.net/?id=36401
In the year following their first treatment, patients with head and neck cancer report declines in their physical quality of life but improvements in their mental health quality of life, according to a report in the March issue of Archives of Otolaryngology-Head & Neck Surgery.

Study outlines risk of treatment-resistant infection following facelift surgery
http://www.news-medical.net/?id=36402
About one-half percent of patients undergoing facelift surgery at one outpatient surgical center between 2001 and 2007 developed methicillin-resistant Staphylococcus aureus (MRSA) infections, according to a report in the March/April issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.

Trauma patients likely to experience moderately severe pain 1 year after injuries
http://www.news-medical.net/?id=36405
Most patients have moderately severe pain resulting from their injuries one year after sustaining major trauma, according to a report in the March issue of Archives of Surgery, one of the JAMA/Archives journals.

Obese ICU patients have lower mortality but longer ICU stays
http://www.news-medical.net/?id=36391
Obese intensive care patients do not have a higher ICU death rate than non-obese ICU patients, but they remain in the ICU significantly longer and are intubated significantly longer than non-obese patients, a new study has found.

Advair reduces asthma-related hospitalization and emergency department visits
http://www.news-medical.net/?id=36334
Advair Diskus (fluticasone propionate and salmeterol inhalation powder) was associated with fewer asthma-related hospitalizations and emergency department (ED) visits in pediatric patients when compared to the use of inhaled corticosteroids (ICS) alone, and use of Advair by pediatric and adult patients through the summer was associated with fewer hospitalizations and ED visits in the fall.

Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice
http://www.news-medical.net/?id=36312
Two major eye diseases and leading causes of blindness—age-related macular degeneration and diabetic retinopathy can be reversed or even prevented by drugs that activate a protein found in blood vessel cells, researchers at the University of Utah School of Medicine and several other institutions have announced in a new study.

deCODE obesity study sheds light on how genetic factors contribute to major public health problems
http://www.news-medical.net/?id=36316
In a paper published online in the journal Nature, a team of deCODE scientists detail a major mechanism through which genetic factors contribute to major public health problems.

Transcendental meditation controls high blood pressure
http://www.news-medical.net/?id=36328
Transcendental Meditation is an effective treatment for controlling high blood pressure with the added benefit of bypassing possible side effects and hazards of anti-hypertension drugs, according to a new meta-analysis conducted at the University of Kentucky.

BMI may serve as prognostic tool for advanced, aggressive breast cancers
http://www.news-medical.net/?id=36313
Body Mass Index (BMI), the measure of a person's fat based on their height and weight, may be an effective prognostic tool for specific types of breast cancer, according to research from The University of Texas M. D. Anderson Cancer Center.

Minority, low-income diabetics least likely to monitor their blood glucose
http://www.news-medical.net/?id=36331
Black and Hispanic adults with insulin-treated diabetes are less likely than whites to monitor their blood glucose, according to a new study presented at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

Australian men care about their health
http://www.news-medical.net/?id=36311
A study of male attitudes to health and how they use health services, published in the online open access journal, BMC Health Services Research, challenges the usual stereotype that men are uninterested in their health.

How diabetes drives atherosclerosis
http://www.news-medical.net/?id=36301
Researchers have discovered how diabetes, by driving inflammation and slowing blood flow, dramatically accelerates atherosclerosis, according to research to be published in the March 14 edition of the journal Circulation Research. Experts once believed that atherosclerosis, or hardening of the arteries, developed when too much cholesterol clogged arteries with fatty deposits called plaques.

Simple laboratory test predicts risk of kidney injury after surgery
http://www.news-medical.net/?id=36280
A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

Colorectal cancer screening increasing among U.S. adults
http://www.news-medical.net/?id=36282
The percentage of U.S. adults aged 50 years and older getting screened for colorectal cancer is increasing according to a study released by the Centers for Disease Control and Prevention's (CDC) Morbidity and Mortality Weekly Report.

Giving up smoking during pregnancy boosts chances of easygoing child
http://www.news-medical.net/?id=36290
Giving up smoking during pregnancy may boost the chances of giving birth to an easy going child, indicates research in the Journal of Epidemiology and Community Health.

Study explains fundamental process of tumor growth
http://www.news-medical.net/?id=36300
Nearly 80 years ago, scientist Otto Warburg observed that cancer cells perform energy metabolism in a way that is different from normal adult cells.

Low cost tactics improve medication use after heart attack
http://www.news-medical.net/?id=36274
Direct-to-patient communication about the importance of continuing prescription drug treatment after a heart attack is a simple, low-cost way to increase the likelihood of patients adhering to life saving therapies at least four out of every five days.

MGH initiates trial to reverse type 1 diabetes
http://www.news-medical.net/?id=36277
Scientists at the Massachusetts General Hospital (MGH) have initiated a phase 1 clinical trial to reverse type 1 diabetes.

Lilly and Transition Therapeutics announce licensing and collaboration agreement
http://www.news-medical.net/?id=36272
Eli Lilly and Company and Transition Therapeutics Inc. has announced that the two companies have entered into a licensing and collaboration agreement granting Lilly exclusive worldwide rights to develop and commercialize Transition's gastrin based therapies, including the lead compound TT-223, which is currently in early Phase II testing.

Prescribing costs increase dramatically when people reach 65
http://www.news-medical.net/?id=36288
Prescribing costs increase dramatically when people reach 65, according to a detailed analysis of more than five million patients published in the March issue of the British Journal of Clinical Pharmacology.

A long-term survival offered by resection of solid-pseudopapillary tumor of the pancreas?
http://www.news-medical.net/?id=36255
The article published in volume 14 issue 6 of World Journal of Gastroenterology reports on one patient who presented to Dr Cosimo Sperti of University of Padua, Padova, Italy, in 2001 after an exploratory laparotomy performed in another hospital for an unresectable pancreatic cystic mass that had infiltrated the portal vein.

Artificial butter chemical acetyl harmful to lungs
http://www.news-medical.net/?id=36295
A new study shows that exposure to a chemical called diacetyl, a component of artificial butter flavoring, can be harmful to the nose and airways of mice.

A new finding in liver transplantation and antifibrinolytics?
http://www.news-medical.net/?id=36256
Orthotopic liver transplantation (OLT) is associated with severe bleeding and considerable transfusion requirements.

Heavier alcohol consumption increases the risk of esophageal squamous cell carcinoma
http://www.news-medical.net/?id=36259
Heavier alcohol consumption increases the risk of esophageal squamous cell carcinoma (ESCC). There are synergetic interactions among alcohol drinking and ALDH2, ADH1B, CYP2E1 genotypes.

First clinical trial data of a fully bioabsorbable drug-eluting stent
http://www.news-medical.net/?id=36304
Data published today in The Lancet from ABSORB, the world's first clinical trial of a fully bioabsorbable drug eluting stent for the treatment of coronary artery disease, demonstrated no stent thrombosis, no clinically driven target lesion revascularizations (re-treatment of a diseased lesion), and a low (3.3 percent) rate of major adverse cardiac events (MACE) in 30 patients out to one year.

Treatment for substance abuse vital to reduce prison recidivism rate
http://www.news-medical.net/?id=36306
For newly released prisoners, successful substance abuse treatment on the outside may be the most important factor in keeping them from returning to jail - trumping issues such as transitional housing and finding a job.

Study confirms link between colds and ear infections
http://www.news-medical.net/?id=36292
A new five-year study at the University of Texas Medical Branch at Galveston confirms the suspected close link between the two most common diseases of young children: colds and ear infections.

Study shows Parkinson's disease drug dopamine might work in cancer patients
http://www.news-medical.net/?id=36275
A study published in the March 13 online issue of The Journal of Clinical Investigation shows that dopamine, a drug currently used to treat Parkinson's disease and other illnesses, also might work in cancer patients.

New drug protects nerve cells from damage in mice
http://www.news-medical.net/?id=36278
Multiple sclerosis (MS) is a chronic inflammatory disease of the brain and spinal cord. Individuals with MS develop progressive neurological disability, and this is thought to be caused by degradation of the nerve cells.

Psychological intervention reduces postembolization pain
http://www.news-medical.net/?id=36289
Psychological intervention has been shown to reduce the postembolization pain during hepatic arterial chemoembolizatiom therapy.

Damaged veins heal faster with heparin treatment, laboratory study finds
http://www.news-medical.net/?id=36263
A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center.

Long-term muscle improvements shown in gene therapy study in mice
http://www.news-medical.net/?id=36273
Injecting a gene responsible for making a specific protein into a mouse that's used as a model for muscular dystrophy can lead to long-term improvements in the animal's muscle size and strength, a new study shows.

A tumor of the pancreas mimicked by colonic duplication
http://www.news-medical.net/?id=36257
A case of cystic colonic duplication in an adult mimicked a tumor of the pancreas and the diagnosis was established by histopathological examination of the resected specimen after distal pancreatectomy.

Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?
http://www.news-medical.net/?id=36296
Surgery is the only curative treatment in patients with bile duct cancer.

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