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PUTTING BREAKING MEDICAL NEWS INTO PRACTICE^™

Wednesday March 19, 2008

TODAY'S HEADLINES
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For the latest news, features, columns, video and audio reports and more, visit our home page at www.medpagetoday.com

SIR: Acute GvHD Relieved by Catheter-Delivered Steroids

WASHINGTON -- Catheter-delivered steroids may be able to reverse acute graft-versus-host disease in allogeneic hematopoietic transplant patients not helped by systemic steroids, a New York researcher said here. full story

http://www.medpagetoday.com/MeetingCoverage/SIRMeeting/dh/8800

Survey Time to ban imported drugs?

With the recent heparin troubles as a case in point, is it time to stop importing biologics? Vote

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Practice Pointers

SIR: Elderly Do Well in Arterial Procedures

WASHINGTON -- There is no age limit for diagnostic angiography and percutaneous arterial procedures such as stenting, said researchers here. full story

http://www.medpagetoday.com/MeetingCoverage/SIRMeeting/dh/8804

AAAAI: New Therapies on Horizon for Angioedema Attacks

PHILADELPHIA -- Several new, specific treatments for hereditary angioedema may soon be available in the U.S., researchers said here. full story

http://www.medpagetoday.com/MeetingCoverage/AAAAIMeeting/dh/8810

FDA Cites Excess Strokes with COPD Medicine
ROCKVILLE, Md. -- The FDA alerted clinicians today of pooled data from 29 placebo-controlled trials of tiotropium (Spiriva HandiHaler) that revealed excess strokes among chronic obstructive pulmonary disease patients on active treatment. full story

http://www.medpagetoday.com/ProductAlert/Prescriptions/dh/8808

Direct Link Ties HDL-Related Gene to Cardiovascular Risk

CLEVELAND -- Cardiac events and mortality were significantly associated with genotypic variations in paraoxonase 1 (PON1), which contributes to the anti-inflammatory and antioxidant activities of high-density lipoprotein (HDL), investigators here reported. full story

http://www.medpagetoday.com/Cardiology/CoronaryArteryDisease/dh/8802

Pain Hampering Daily Life Still a Factor a Year After Major Trauma

SEATTLE -- For a majority of patients recovering from major trauma, there is still pain a year later that is likely to interfere with daily activities, according to investigators here. full story

http://www.medpagetoday.com/Neurology/PainManagement/dh/8807

FDA Cites High Mortality with Stent Used to Repair AAA
ROCKVILLE, Md. -- Mortality was substantially higher in patients who had an AneuRx Stent Graft implanted to prevent abdominal aortic aneurysm rupture than in patients who had a surgical repair, according to the FDA. full story

http://www.medpagetoday.com/ProductAlert/DevicesandVaccines/dh/8806

AAAAI: Combination Inhalers for Asthma Lower Death Risk

PHILADELPHIA -- For asthma patients who need inhaled corticosteroids and long-acting beta agonists, combination products appear to be safer than separate inhalers, a researcher said here. full story

http://www.medpagetoday.com/MeetingCoverage/AAAAIMeeting/dh/8803

SGO: Knowledge of HPV Vaccine Found Uneven Among Primary-Care Specialties

TAMPA, Fla. -- Internists’ and family physicians’ knowledge about human papillomavirus vaccine lags significantly behind that of colleagues in pediatrics and obstetrics-gynecology, according to a survey reported here. full story

http://www.medpagetoday.com/MeetingCoverage/SGO/dh/8790

Head and Neck Cancer Treatment Erodes Quality of Life

ANN ARBOR, Mich. -- Although head and neck cancer patients had improved mental health scores a year after diagnosis and treatment, their quality of life, particularly the ability to eat, had declined markedly, a study here found. full story

http://www.medpagetoday.com/HematologyOncology/OtherCancers/dh/8799

SIR: Percutaneous Cryoablation Effective Against Kidney Cancer

WASHINGTON -- Percutaneous cryoablation stops kidney cancer cold, researchers said here. full story

http://www.medpagetoday.com/MeetingCoverage/SIRMeeting/dh/8782

Human Growth Hormone May Not Improve Athletic Performance

SAN JOSE, Calif. -- Athletes who turn to human growth hormone to boost performance may get bigger, but their muscles don’t work any better, a systematic review found. full story

http://www.medpagetoday.com/Endocrinology/GeneralEndocrinology/dh/8797

MRSA Implicated in Majority of Post-Facelift Infections

NEW YORK -- Although surgical-site infections after face-lift procedures are uncommon, those that occur are usually caused by methicillin-resistant Staphylococcus aureus, making them difficult to treat. full story

http://www.medpagetoday.com/Surgery/PlasticSurgery/dh/8796

SIR: ’Chemosurgery’ Saves Eyes in Retinoblastoma

WASHINGTON -- Lives and eyes in advanced retinoblastoma can be preserved by catheter-delivered chemotherapy, a researcher reported here. full story

http://www.medpagetoday.com/MeetingCoverage/SIRMeeting/dh/8789

CME SPOTLIGHT

Controversies and Consensus in the Management of HIV: Interactive Debates
Are NNRTI- or PI-based regimens the best choice for initial ARV therapy? If a patient is failing therapy, when should you switch? Do treatment experienced patients require 2 or 3 active ARV agents? Join us for thoughtful debates and lively discussion led by a panel of HIV experts.
Source: AdvancMed [more]

Adequate Relief: Optimal Opioid Dosing and Side-Effect Management for Long-Term Care Patients
This CME/CE certified monograph addresses optimal opioid dosing and side effect management for long-term care patients.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Managing the Symptomatic Menopausal Patient in Primary Care: A Case-Based Approach
This interactive CME activity provides practical recommendations and the latest clinical evidence to improve the personalized care a women receives during menopause.
Source: Interstate Postgraduate Medical Association and MEV Healthcom, Inc. [more]

Depressive Symptoms in an Elderly Patient: Sorting Out the Alternatives
The following certified educational series is designed to help primary care clinicians recognize the signs and symptoms of major depressive disorders. The participant will review evidence-based management strategies for elderly patients with major depressive disorders and medical co- morbidities.
Source: The University of Pennsylvania School of Medicine [more]

Emerging Trends in the Treatment of Renal Cell Carcinoma
Drs. Michael B. Atkins, Bernard J. Escudier, and Gary R. Hudes lead this CME activity which examines current and evolving standards of care for the treatment of early stage and advanced renal cell carcinoma; best practices for optimal patient outcomes are also covered.
Source: The Physicians Academy For Clinical and Management Excellence [more]

A Customized Approach to the Management of Hepatitis B Viral Infection
This CME journal supplement is case-based and provides practical approaches to halting the natural history of HBV infection, to tailoring HBV therapy, and to treating pregnant or immunosuppressed patients infected with HBV.
Source: AdvancMed [more]

Taking the Path of Least Resistance to Improved Clinical Outcomes from Surgical Site Infections
Join Dr. Sawyer for an innovative and in-depth CME-certified Activity on taking the path of least resistance to improve clinical outcomes from surgical site infections.
Source: CME Enterprise [more]

Bridging Cultural Differences to Improve HBV Treatment in Asian and Other Diverse Communities
This CME/CE program features state-of-the-science information on hepatitis B virus (HBV) disease burden, HBV replication and transmission, screening for HBV, treatment options and management of HBV.
Source: Projects In Knowledge [more]

JOURNAL DOWNLOADS

First-line SUTENT® data recently published in NEJM
Read first-line SUTENT data in the New England Journal of Medicine. Get it at SUTENThcp.com Source: Pfizer [more]

RESOURCES

Now Approved: A new development in the treatment of hypertension.
Now approved from Forest Laboratories: Bystolic (nebivolol). A novel beta blocker for the treatment of hypertension. Click here to learn more. Source: Forest Labs [more]

Explore the Possibilities in Type 2 Diabetes.
Explore the Possibilities in Type 2 Diabetes. Source: Merck [more]

Access information on more than 150 Pfizer products at PfizerPro.com
Pfizer medicines have a new home on the Web. Visit PfizerPro.com for information on more than 150 Pfizer products. Convenient access to full prescribing information, scientific literature, professional resources, patient education material, and more. Source: Pfizer [more]

Take a closer look at all 3 major lipids and cardiovascular risk. HDL, LDL and TG levels may be independently associated with cardiovascular risk.
Visit www.totallipds.com, a new source of information for health care professionals, about dyslipidemia, all 3 lipids, and cardiovascular risk. Source: Merck [more]

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IAS Meeting

IAS: Novel HIV Entry Blocker Found Safe and Powerful

IAS: New Drugs Effective Against HIV Resistance

ICAAC Meeting

ICAAC: Antibiotic Resistance Gene Goes West

HIV/AIDS

Herpes Treatment Lowers HIV In Co-Infected Men

ACR Meeting

ACR: RA Severity Linked to Infections and Anemia

ACR: Early Therapy for Inflammatory Arthritis Yields High Remission Rates

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