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PUTTING BREAKING MEDICAL NEWS INTO PRACTICE^™

Thursday March 27, 2008

TODAY'S HEADLINES
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Did you know that you can earn CME/CE credit by reading our news reports? Look for the CME designation after the article title.

FDA’s Rush to Meet Review Deadlines Called Safety Compromise

CAMBRIDGE, Mass. -- The FDA hurried some drug approvals to meet deadlines imposed by Congress, resulting in safety problems after the products entered clinical use, researchers here alleged. full story

http://www.medpagetoday.com/PublicHealthPolicy/HealthPolicy/tb/8906

Survey Does China’s Move Ease Worries?

The Chinese government has announced that it’s increasing supervision over the production of heparin. Does that alleviate some of the worry about importing biologics? Vote

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Rx for Fun

Belly Fat May Pose Dementia Risk

OAKLAND, Calif. -- A middle-age paunch may heighten the risk of dementia in older age, according to an analysis of almost 6,600 adults followed for more than three decades. full story

http://www.medpagetoday.com/PrimaryCare/Obesity/tb/8910

Skipping Breakfast Counterproductive for Teens Concerned about Weight

MINNEAPOLIS, March 26 -- Teenagers who start the day with breakfast may be less likely to gain weight than those who skip the meal, researchers found. full story

http://www.medpagetoday.com/Pediatrics/Obesity/tb/8914

Mechanical Ventilation Weakens the Lungs

PHILADELPHIA, March 26 -- A patient’s diaphragm may atrophy quickly when mechanical ventilation takes all the pressure off the lungs, researchers found. full story

http://www.medpagetoday.com/Surgery/GeneralSurgery/tb/8892

Risk of Caesarean Delivery Linked to Cervical Length Mid-Pregnancy

CAMBRIDGE, England -- Women are likely to need a Caesarean delivery at term if, midway through pregnancy, the cervix is 40 mm or longer, researchers here found. full story

http://www.medpagetoday.com/OBGYN/Pregnancy/tb/8908

FDA Wants Longer Studies and Harder Endpoints for Drug-Eluting Stent Approvals
ROCKVILLE, Md. -- The FDA proposed today that new drug-eluting stents accumulate at least 12 months of data, with twice that experience for a substantial number of patients, before the devices are submitted for approval. full story

http://www.medpagetoday.com/Cardiology/PCI/tb/8913

Group-Randomized Cancer Trials Often Statistically Flawed

COLUMBUS, Ohio -- Design and statistical flaws in group-randomized clinical trials are common and can lead to inaccurate conclusions about a cancer intervention’s efficacy, investigators here concluded. full story

http://www.medpagetoday.com/PublicHealthPolicy/ClinicalTrials/tb/8912

Male Contraception Hormone Combination Gains Standing

LOS ANGELES -- Combining androgens and progestins appears to provide reliable and reversible contraception for most men, researchers here said. full story

http://www.medpagetoday.com/OBGYN/Pregnancy/tb/8911

FDA Issues Alert on Risks with Supplements Marketed for Erectile Dysfunction
ROCKVILLE, Md. -- Two dietary supplements marketed over the Internet as purported erectile dysfunction treatments may contain ingredients that can cause dangerous hypotension, the FDA has warned. full story

http://www.medpagetoday.com/PrimaryCare/AlternativeMedicine/tb/8905

Imaging Results Have Little Effect on Prophylactic Mastectomy Decision

NIJMEGEN, The Netherlands -- Many women who have a breast cancer susceptibility gene may make up their minds about prophylactic treatment before receiving an MRI or mammography result. full story

http://www.medpagetoday.com/HematologyOncology/BreastCancer/tb/8904

Early Lung Cancer Study Found Funded by Tobacco Money
NEW YORK -- Tobacco-industry money has been revealed as the funding source of a widely publicized study that reported annual CT-screening of smokers and former smokers could save lives by detecting lung cancer at its earliest stage. full story

http://www.medpagetoday.com/PrimaryCare/Smoking/tb/8903

CME SPOTLIGHT

Targeted Cancer Therapy From Trial To Clinic
Join Drs. Balducci, Atkins, Cantley, and Herbst for an innovative and in-depth CME-certified Activity on how integration of targeted and conventional therapies for treating cancer is improving patient outcomes.
Source: The Physicians Academy For Clinical and Management Excellence [more]

Controversies and Consensus in the Management of HIV: Interactive Debates
Are NNRTI- or PI-based regimens the best choice for initial ARV therapy? If a patient is failing therapy, when should you switch? Do treatment experienced patients require 2 or 3 active ARV agents? Join us for thoughtful debates and lively discussion led by a panel of HIV experts.
Source: AdvancMed [more]

A Customized Approach to the Management of Hepatitis B Viral Infection
This CME journal supplement is case-based and provides practical approaches to halting the natural history of HBV infection, to tailoring HBV therapy, and to treating pregnant or immunosuppressed patients infected with HBV.
Source: AdvancMed [more]

Bridging Cultural Differences to Improve HBV Treatment in Asian and Other Diverse Communities
This CME/CE program features state-of-the-science information on hepatitis B virus (HBV) disease burden, HBV replication and transmission, screening for HBV, treatment options and management of HBV.
Source: Projects In Knowledge [more]

Medical and Surgical Management of Aortic Valve Disease
Join Dr. Joseph E. Bavaria, MD and the team of University of Pennsylvania cardiology and surgery specialists in reviewing of all the important topics related to aortic valve conditions that a cardiovascular clinician faces on a daily basis.
Source: University of Pennsylvania School of Medicine [more]

Genital HPV and HPV Vaccines: Winning acceptance among adolescents and their parents
HPV is a highly prevalent sexually transmitted infection, most common in sexually active women under the age of 25. The following free educational activity is designed to educate physicians about the most common types of genital HPV and review the safety and efficacy of utilizing HPV vaccines.
Source: SciMed New York [more]

Emerging Trends in the Treatment of Renal Cell Carcinoma
Drs. Michael B. Atkins, Bernard J. Escudier, and Gary R. Hudes lead this CME activity which examines current and evolving standards of care for the treatment of early stage and advanced renal cell carcinoma; best practices for optimal patient outcomes are also covered.
Source: The Physicians Academy For Clinical and Management Excellence [more]

JOURNAL DOWNLOADS

First-line SUTENT® data recently published in NEJM
Read first-line SUTENT data in the New England Journal of Medicine. Get it at SUTENThcp.com Source: Pfizer [more]

Efficacy Data for CTCL Published in JCO
Efficacy Data for CTCL Published in JCO. Source: Merck. [more]

RESOURCES

Why not provide greater LDL-C efficacy for your appropriate newly initiated patients?
View the data on 50% mean reduction right from the start. Source: Merck [more]

Take a closer look at all 3 major lipids and cardiovascular risk. HDL, LDL and TG levels may be independently associated with cardiovascular risk.
Visit www.totallipds.com, a new source of information for health care professionals, about dyslipidemia, all 3 lipids, and cardiovascular risk. Source: Merck [more]

Featured Job Opportunities from MedJobs Today

Urology, Arkansas
Position consists of clinic, hospital consults, and surgery, and there is ER coverage with a minimum of 10 days per month.
http://www.medjobstoday.com/seeker/job_detail.cfm?jobid=17311&refsrc=dh
Urology, New York
A teaching facility in upstate New York is seeking two urologists to place for clinic and call coverage.
http://www.medjobstoday.com/seeker/job_detail.cfm?jobid=17590&refsrc=dh
Urology, Wisconsin
This opening is for weekend call coverage from Friday evening at 5pm to Monday morning at 8am.
http://www.medjobstoday.com/seeker/job_detail.cfm?jobid=17779&refsrc=dh

Visit MedJobs Today.com to search for a new job!

ASCO Meeting

ASCO: Neoadjuvant Bevacizumab (Avastin) Safe for Colorectal Cancer Liver Metastases

ASCO: African Americans Fare Worse in Bevacizumab (Avastin) Colorectal Cancer Study

ADA Meeting

ADA: Investigational Diabetes Drug Rids Glucose Via Urine

ICAAC Meeting

ICAAC: Tampon Coating Reduces Menstrual Toxic Shock Toxin

ICAAC: Day Care Safer Thanks to Vaccines

IASLC Meeting

IASLC: Hand-Rolled Cigarettes More Carcinogenic than Store Bought

Get tools, resources & information about Gleevec matching the experience of attendees of the 2007 ASH Annual Meeting.

Did you miss the Gleevec booth at the 2007 ASH Meeting? Get tools, resources and information about Gleevec via a fully interactive virtual exhibit booth, matching the experience of attendees of the 2007 ASH Annual Meeting.

Source: Novartis Oncology.

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