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Medical Studies/Trials News Fasting for two days protects healthy cells against chemotherapy
http://www.news-medical.net/?id=36819
The chemotherapy worked as intended on cancer, extending the lifespan of mice injected with aggressive human tumors, reported a group led by Valter Longo of the University of Southern California.
Angina drug ranolazine shows promise for heart rhythm disorders
http://www.news-medical.net/?id=36821
A recently approved angina drug may also represent a powerful new treatment for a rare hereditary syndrome that places teens at risk for sudden cardiac death, according to research presented at the 57th Annual Scientific Sessions of the American College of Cardiology (ACC) in Chicago.
Significant reductions in mortality shown using blood pressure-lowering treatment in very elderly
http://www.news-medical.net/?id=36847
Lowering the blood pressure of elderly patients could cut their total mortality by a fifth and their rate of cardiovascular events by a third, according to a new study presented at the American College of Cardiology in Chicago and published simultaneously in the New England Journal of Medicine.
Study looks at use of powerful anticoagulants to prevent pulmonary embolism
http://www.news-medical.net/?id=36822
Current US guidelines for the prescription of potent anticoagulants by surgeons who perform joint replacement operations could be doing patients more harm than good, according to Dr. Nigel Sharrock and his team from the Hospital for Special Surgery in New York.
Study shows Actos prevented progression of atherosclerotic plaque volume in patients
http://www.news-medical.net/?id=36833
New data from a clinical trial using intravascular ultrasound (IVUS) technology found that in patients living with type 2 diabetes, ACTOS (pioglitazone HCl) reduced the atherosclerotic burden in the coronary arteries compared to glimepiride, and prevented progression compared to baseline.
Lebanese study looks at mental disorders and their relation to exposure to war
http://www.news-medical.net/?id=36829
In the first study in the Arab world to document mental illness and treatment on a national level, researchers from Lebanon have described the prevalence of mental disorders and their relation to exposure to war.
Two drug combo blood pressure therapy lowers cardiovascular risk
http://www.news-medical.net/?id=36818
An international blood pressure study comparing two single-pill drug combinations has yielded results so significant that the study has been stopped early and the researchers say their findings might alter the way high blood pressure is treated worldwide.
Matrix registry probes adherence to clopidogrel at 1 year
http://www.news-medical.net/?id=36828
A large community-based registry of patients treated with drug-eluting stents is providing important insight into how long patients with complex coronary artery disease typically stick to their doctors' orders to take clopidogrel, a drug that prevents unwanted blood clots; why they stop taking the drug; and the long-term consequences of that decision.
New blood pressure drug telmisartan has fewer side effects
http://www.news-medical.net/?id=36832
A major Canadian-led global study has found that a new blood pressure medication is effective in reducing cardiovascular death, with fewer side effects than the current standard of care.
Lung transplants not dangerous for children with cystic fibrosis, after all
http://www.news-medical.net/?id=36859
Responding to a study published in the New England Journal of Medicine, which concluded that lung transplants were harmful for children with cystic fibrosis, articles published in the latest issue of Pediatric Transplantation refute the conclusions and argue that the highly influential research was severely flawed.
A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics
http://www.news-medical.net/?id=36863
Results of a randomised trial published in PLoS Medicine show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's disease.
Disappointing resuts for pimecrolimus, investigational anti-restenosis drug
http://www.news-medical.net/?id=36857
A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance in a multicenter clinical trial, but the multi-reservoir stent that was used to deliver the drug is still considered promising.
Study results on novel drug-eluting stent coated with a biodegradable polymer
http://www.news-medical.net/?id=36867
"Real-world" use of a novel drug-eluting stent coated with a biodegradable polymer is associated with good clinical outcomes, according to one-year data from a large international registry.
Eli Lilly starts trial of treatment of mild to moderate Alzheimer's disease
http://www.news-medical.net/?id=36858
Eli Lilly and Company has announced the start of a Phase III clinical trial studying LY450139, an investigational gamma secretase inhibitor for the treatment of mild to moderate Alzheimer's disease.
Tai Chi improves control of type 2 diabetes
http://www.news-medical.net/?id=36873
Tai Chi exercises can improve the control of type 2 diabetes, suggests a small study, published ahead of print in the British Journal of Sports Medicine.
Cerebral microbleeds more common than previously thought
http://www.news-medical.net/?id=36848
New research shows cerebral microbleeds, which are lesions in the brain, are more common in people over 60 than previously thought.
Childhood leukemia survivors struggle with long-term comorbidities
http://www.news-medical.net/?id=36849
Survival rates of childhood cancers, especially leukemia, have improved greatly in the past three decades, but survivors of this disease still seem to face many health and lifestyle challenges as young adults.
Diabetics have same risk for heart attack, stroke or death from cardiovascular diseases
http://www.news-medical.net/?id=36853
People with diabetes have the same high risk for heart attack or stroke or cardiovascular death as people who've already had a heart attack, researchers reported in Circulation: Journal of the American Heart Association.
New blood pressure drug Micardis (Telmisartan) good at reducing deaths from heart attacks
http://www.news-medical.net/?id=36844
An international team of researchers have found that a new blood pressure medication is as effective in reducing cardiovascular death, with fewer side effects than the current treatments offered.
Hypertension treatment for the elderly cuts the risk of heart disease and stroke
http://www.news-medical.net/?id=36836
New research from Britain suggests that when the elderly are treated for hypertension (high blood pressure) the medication reduces their risk of heart disease, stroke and even death.
Fasting could offer protection from chemotherapy effects
http://www.news-medical.net/?id=36835
A new study is suggesting that short-term fasting could help protect cancer patients against the effects of chemotherapy.
Fatality rates increase with repeal of helmet laws
http://www.news-medical.net/?id=36823
Since 1975, more than 100,000 motorcycle riders in America have died in crashes.
Relaxation response training may improve control of hard-to-treat systolic hypertension
http://www.news-medical.net/?id=36776
Adding the relaxation response, a stress-management approach, to other lifestyle interventions may significantly improve treatment of the type of hypertension most common in the elderly.
Discrimination against overweight people is as prevalent as racial discrimination
http://www.news-medical.net/?id=36791
Discrimination against overweight people - particularly women - is as common as racial discrimination, according to a study by the Rudd Center for Food Policy & Obesity at Yale University.
Repeated episodes of stent thrombosis common
http://www.news-medical.net/?id=36786
When a clot develops inside a coronary stent, it can block blood flow to the heart, potentially causing a heart attack or even death.
Post-traumatic stress disorder associated with more, longer hospitalizations
http://www.news-medical.net/?id=36775
Researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) have found post-traumatic stress disorder (PTSD) is associated with more hospitalizations, longer hospitalizations and greater mental healthcare utilization in urban primary care patients.
Cooperative classrooms lead to better friendships, higher achievement in young adolescents
http://www.news-medical.net/?id=36801
Students competing for resources in the classroom while discounting each others' success are less likely to earn top grades than students who work together toward goals and share their success, according to an analysis of 80 years of research.
Study gives nod to drug-eluting stents in heart attack
http://www.news-medical.net/?id=36815
Although drug-eluting stents have become widely used for the treatment of stable coronary artery disease, many cardiologists choose bare-metal stents for patients with heart attack, or myocardial infarction (MI), citing conflicting data about the safety and effectiveness of drug-eluting stents in this patient group.
Largest ever analysis of DES data demonstrates safety, efficacy in on-and-off-label use
http://www.news-medical.net/?id=36816
The Cardiovascular Research Foundation (CRF) will present results of the largest meta-analysis to date comparing mortality rates for drug-eluting stents (DES) versus bare metal stents (BMS) at the Drug-Eluting Stent Revolution VII meeting tomorrow evening in Chicago.
Being born bottom first is inherited
http://www.news-medical.net/?id=36797
A baby is twice as likely to be born bottom first if either or both the parents were themselves breech deliveries, according to a study published ahead of print on bmj.com.
Early family choices may be a productive option for many young adults
http://www.news-medical.net/?id=36807
Young people are always encouraged to complete their education and postpone marriage and children to achieve more rewarding lifestyles.
Gene mutations tied to immune comeback during therapy for HIV-1
http://www.news-medical.net/?id=36811
A new study by U.S. scientists provides compelling evidence that two genes are linchpins in defining the course of immune restoration in HIV-positive individuals undergoing virus-suppressing therapy.
New genetic clues to diabetes
http://www.news-medical.net/?id=36817
An international team that included scientists from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today reported it has identified six more genetic variants involved in type 2 diabetes, boosting to 16 the total number of genetic risk factors associated with increased risk of the disease.
Communication key to a healthy heart
http://www.news-medical.net/?id=36799
When it comes to matters of the heart, many experts say that communication is the key to a healthy relationship.
Comparison of anticoagulants for angioplasty show similar outcomes
http://www.news-medical.net/?id=36800
In a comparison of anticoagulants and stents for use with angioplasty following a heart attack, the anticoagulants abciximab and tirofiban had similar outcomes for some cardiac measures within 90 minutes after the procedure, while patients who received stents that released the drug sirolimus had a lower risk of major adverse cardiac events within 8 months than patients who received uncoated stents, according to a JAMA study being released early online March 30 to coincide with its presentation at the annual conference of the American College of Cardiology.
Hairdressers at an increased risk for cancers
http://www.news-medical.net/?id=36768
According to the World Health Organisation (WHO), hair dyes and other chemicals place hairdressers at an increased risk for cancer.
Middle-age spread a potent predictor of dementia
http://www.news-medical.net/?id=36762
According to a new study overweight or obese people are at an increased risk of developing dementia or Alzheimer's disease.
Long-term use of mechanical ventilation contributes to the deterioration of human diaphragm muscle
http://www.news-medical.net/?id=36736
A new study by University of Pennsylvania School of Medicine shows, for the first time in humans, that ventilators combined with diaphragm disuse contributes to muscle atrophy in the diaphragm in as little as eighteen hours.
Umbilical cord blood cell therapy may reduce signs and symptoms of Alzheimer's disease
http://www.news-medical.net/?id=36757
Targeted immune suppression using human umbilical cord blood cells may improve the pathology associated with Alzheimer's disease, a new study in a mouse model of this currently untreatable neurodegenerative condition reports.
Study shows that a larger abdomen in midlife increases risk of dementia
http://www.news-medical.net/?id=36730
People in their 40s with larger stomachs have a higher risk for dementia when they reach their 70s, according to a study published in the March 26, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology .
The upside of anger
http://www.news-medical.net/?id=36750
Here's a maxim from the "duh" department: People typically prefer to feel emotions that are pleasant, like excitement, and avoid those that are unpleasant, like anger.
Partners can help or hinder attempts at changing diet
http://www.news-medical.net/?id=36742
For people trying to make a change in their diet, significant others generally play a positive and supportive role, but sometimes respond in negative ways, according to a study in the March/April Journal of Nutrition Education and Behavior.
Study shows lifetime effects of pediatric liver transplants
http://www.news-medical.net/?id=36749
Parents of pediatric liver transplant recipients report lower health-related quality of life for their children two years after the surgery, compared to reports from the parents of healthy children.
Groundbreaking study validates Pittsburgh Compound-B in identifying Alzheimer's disease brain toxins
http://www.news-medical.net/?id=36751
A groundbreaking study conducted by University of Pittsburgh Alzheimer's disease researchers reported in the journal Brain (currently online) confirms that Pittsburgh Compound-B (PiB) binds to the telltale beta-amyloid deposits found in the brains of patients with Alzheimer's disease.
PET confirmed as valuable cancer diagnostic and disease-staging tool
http://www.news-medical.net/?id=36743
The recent release of data by the National Oncologic PET Registry (NOPR) showing that positron emission tomography (PET) produced scans revealing disease at a molecular level, which then caused physicians to change treatment plans for more than one-third of participating patients, has corroborated decades of nuclear medicine research.
Gambling addicts don't learn from their mistakes
http://www.news-medical.net/?id=36717
Gambling addicts don't learn from their mistakes, according to a study published today in the open access journal Clinical Practice and Epidemiology in Mental Health.
More evidence natural antioxidant found in grape skins and red wine kills cancer
http://www.news-medical.net/?id=36737
Rochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function.
New insights into anti-cancer effects of NSAIDs
http://www.news-medical.net/?id=36741
Researchers at the National Sun Yat-Sen University and Kaohsiung Medical University, Kaohsiung, Taiwan have revealed a new mechanism by which nonsteroidal anti-inflammatory drugs (NSAIDs) attenuate tumor invasion and metastasis.
Potential new genetic markers for Crohn's disease
http://www.news-medical.net/?id=36733
What is believed to be the largest study of its kind for the genetic roots of inflammatory bowel diseases has suggested new links to Crohn's Disease as well as further evidence that some people of Jewish descent are more likely to develop it.
Calcium deposits in coronary arteries provide a strong predictor for possible future heart problems
http://www.news-medical.net/?id=36718
Calcium deposits in coronary arteries provide a strong predictor for possible future heart attacks and cardiac diseases, and detecting such deposits can be valuable for promoting overall cardiac health, according to a study led by the University of California, Irvine and appearing in the March 28 issue of the New England Journal of Medicine.
Dental chair a possible source of neurotoxic mercury waste
http://www.news-medical.net/?id=36719
Mercury is a large component of dental fillings, but it is not believed to pose immediate health risks in that form.
Study shows use of asthma medication contradicts guidelines
http://www.news-medical.net/?id=36704
A study has found only 16 per cent of the 352,082 Australians who filled a prescription for asthma preventer medications for the first time during the period July 2004 to June 2005, went on to use them regularly.
Discovery of important links between heart failure and complications during non-cardiac surgery
http://www.news-medical.net/?id=36695
In the largest study of its kind in the U.S., researchers from Duke University have identified a possible "perfect storm" of factors pushing heart failure to the forefront of risks for complications after surgery in the elderly.
When your antidepressants don't work
http://www.news-medical.net/?id=36700
should you switch to a different medication from the same class or should you try an antidepressant medication that has a different mechanism of action?
Partners can help or hinder attempts at changing diet
http://www.news-medical.net/?id=36682
For people trying to make a change in their diet, significant others generally play a positive and supportive role, but sometimes respond in negative ways, according to a study in the March/April Journal of Nutrition Education and Behavior ( http://www.jneb.org/ ).
Antidepressant use linked to type 2 diabetes
http://www.news-medical.net/?id=36655
While analyzing data from Saskatchewan health databases, Lauren Brown, researcher with the U of A's School of Public Health, found people with a history of depression had a 30 per cent increased risk of type 2 Diabetes.
Radiologists use special MRI to identify brain cancer early
http://www.news-medical.net/?id=36686
A special type of magnetic resonance imaging (MRI) can depict changes in blood volume in the brain that often precede cancerous transformation of brain tumors, according to a new study published in the April issue of the journal Radiology.
Hospitality industry worst for alcohol-related problems
http://www.news-medical.net/?id=36670
A new analysis of government data finds that 15 percent of employees in the hospitality industry suffer from serious alcohol-related problems.
Youth's social problems contribute to anxiety and depression
http://www.news-medical.net/?id=36703
Socially successful children tend to have fewer symptoms of anxiety or depression, while children with problems such as anxiety and depression tend to have difficulties forming relationships and being accepted by friends.
Coagulation in patients with anxiety disorders
http://www.news-medical.net/?id=36667
"The blood froze in my veins" or "My blood curdled" - these common figures of speech can be taken literally, according to the latest studies.
New insight into how epilepsy may develop
http://www.news-medical.net/?id=36664
An increased number of neuron "hubs" in the epileptic brain may be the root cause for the seizures that characterize the disorder, according to a UC Irvine study.
Exposure to radon gas greatly reduces risk of developing lung cancer
http://www.news-medical.net/?id=36665
Exposure to levels of radon gas typically found in 90 percent of American homes appears to reduce the risk of developing lung cancer by as much as 60 percent, according to a study published in the March 2008 issue of the journal Health Physics.
Beta-blockers heal the heart via the brain when administered during heart failure
http://www.news-medical.net/?id=36668
Up to now, it was thought that beta-blockers work directly on the heart, but the new study shows that the drugs may also act via the brain, suggesting that future therapies to treat cardiovascular disease could be targeting the central nervous system.
Review of group-based cancer trials reveals flaws in studies' design and analysis
http://www.news-medical.net/?id=36688
A new study reviewing 75 group-randomized cancer trials over a five-year stretch shows that fewer than half of those studies used appropriate statistical methods to analyze the results.
Study links chronic illness to coal-mining pollution
http://www.news-medical.net/?id=36697
Pollution from coal mining may have a negative impact on public health in mining communities, according to data analyzed in a West Virginia University research study.
Several methods for enhancing the functioning of defibrillators in cases of heart attack
http://www.news-medical.net/?id=36690
The PhD, defended by engineer Sofia Ruiz de Gauna Gutierrez at the University of the Basque Country (UPV/EHU) puts forward various methods for the elimination of interference caused by compressions and ventilations of cardiopulmonary resuscitation in the context of cardiac defibrillation.
Preterm birth associated with diminished long-term survival, reproduction
http://www.news-medical.net/?id=36684
An analysis of births in Norway found that persons born preterm had an increased risk of death throughout childhood and lower rates of reproduction in adulthood, compared to persons born at term, according to a study in the March 26 issue of JAMA.
Uneven use of less-invasive breast cancer staging test reported
http://www.news-medical.net/?id=36701
The use of sentinel lymph node biopsy (SLNB) during breast cancer surgery increased substantially from 1998 through 2005, according to an article published online March 25 in the Journal of the National Cancer Institute.
Study examines association between type of genetic characteristics and cancer
http://www.news-medical.net/?id=36694
Persons with a certain type of homozygosity (having two identical copies of the same gene, one inherited from each parent), may have a greater predisposition to cancer, according to a study in the March 26 issue of JAMA.
Excessive texting a sign of mental illness
http://www.news-medical.net/?id=36652
According to an expert in the U.S., sending excessive text messages and e-mails may be an indication of a mental illness.
Dieting and medication may reduce blood pressure in patients with hypertension
http://www.news-medical.net/?id=36605
Adults with hypertension may be able to lower their weight and their blood pressure by following a weight-loss diet or using the medication orlistat, according to a meta-analysis of previously published studies reported in the March 24 issue of Archives of Internal Medicine.
Cancer treatments in phase 3 trials successful up to half of the time
http://www.news-medical.net/?id=36603
About one-fourth to one-half of new cancer treatments that reach assessment in phase 3 randomized clinical trials are eventually proven successful, according to a report in the March 24 issue of Archives of Internal Medicine.
Height of pitcher's mound affects throwing motion, injury risk in baseball
http://www.news-medical.net/?id=36632
A study involving several Major League Baseball pitchers indicates that the height of the pitcher's mound can affect the athlete's throwing arm motion, which may lead to potential injuries because of stress on the shoulder and elbow.
Nonalcoholic fatty liver disease related to cardiovascular fitness
http://www.news-medical.net/?id=36631
Patients with nonalcoholic fatty liver disease (NAFLD) have suboptimal levels of cardiovascular fitness, muscle strength, body composition and physical fitness, according to a new study.
Experimental drug SGX393 offers new approach to help control drug resistance in leukemia
http://www.news-medical.net/?id=36617
Oregon Health & Science University Cancer Institute researchers have found that an experimental drug known as SGX393 is effective against Gleevec-resistant chronic myeloid leukemia (CML).
Researchers find evidence of periodontal disease leading to gestational diabetes
http://www.news-medical.net/?id=36615
A study by a New York University dental research team has discovered evidence that pregnant women with periodontal (gum) disease are more likely to develop gestational diabetes mellitus than pregnant women with healthy gums.
Study shows how ignorance can be influential
http://www.news-medical.net/?id=36637
In the current issue of The RAND Journal of Economics, USC researchers provide a challenge to the classic economic model of information manipulation, in which knowing more than anybody else is the key to influence.
Report says anger endemic in British society
http://www.news-medical.net/?id=36648
According to a new report 'anger' is a problem which is endemic in British society, but little is done about it.
GPS enabled cell phones to track risky behaviour in teens
http://www.news-medical.net/?id=36624
How can researchers track where teens go when not in or near home or school to see if this movement has an impact on health-related behavior such as smoking or sexual activity? The answer is through that ubiquitous teen accessory - the cell phone.
Strengthening the tumor-fighting ability of T cells
http://www.news-medical.net/?id=36629
When faced with cancer, the immune system dispatches cells, called T cells, to kill the tumor.
BARACLUDE data show low resistance over 5 years in nucleoside-naive hepatitis B patients
http://www.news-medical.net/?id=36600
New BARACLUDE (entecavir) data presented demonstrated a continued low incidence of resistance in nucleoside-naïve patients through five years of treatment. In the nucleoside-naïve chronic hepatitis B patients analyzed, no additional patient developed resistance in the fifth year (n=108).
Allergies dramatically impact sufferers' moods and how they feel about themselves
http://www.news-medical.net/?id=36572
A new Harris Interactive phone survey conducted among 1,000 allergy sufferers, 1,000 consumers (both allergy sufferers and non-sufferers) and 300 physicians shows that beyond the sneezing, sniffling and watery eyes, allergies also have deep and emotional impacts on a sufferer's mood and self-perceptions.
NanoBio completes interim analysis of phase 2 clinical trial in onychomycosis
http://www.news-medical.net/?id=36569
NanoBio Corporation has announced that it has seen promising results from an interim analysis of its phase 2 study of NB-002, a topical lotion for onychomycosis (nail fungus). Although the details remain confidential, the results clearly justify completing the study, according to NanoBio scientists
Cigarette smokers treated for brain aneurysm with coil embolization at higher risk of recurrence
http://www.news-medical.net/?id=36579
Cigarette smokers who were treated for cerebral aneurysms with coil embolization (blocking of a blood vessel) are at greater risk of developing another aneurysm, say neurological surgeons at Jefferson Hospital for Neuroscience in Philadelphia in the first-known study of its kind.

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